LXQ46 is a novel specific inhibitor of PTP1B, suppressing colony formation in a dose-dependent manner, inducing cell cycle arrest by decreasing the expression of CDK2, CDK4, CDK6, and Cyclin D1, significanty inhibiting PDAC cells migration.
MedKoo Cat#: 533458
Name: LXQ46
CAS#: N/A
Chemical Formula: C23H17Br2NO5
Exact Mass: 544.9473
Molecular Weight: 547.20
Elemental Analysis: C, 50.48; H, 3.13; Br, 29.20; N, 2.56; O, 14.62
The following data is based on the product molecular weight 547.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
