AMPC is a novel potent inhibitor of trefoil factor 3 (TFF3) dimerization, potentiating MEK1/2 inhibition in lung adenocarcinoma, exerting its oncogenic function through upregulation of ARAF and hence enhanced downstream activation of MEK1/2 and ERK1/2.
MedKoo Cat#: 533431
Name: AMPC
CAS#: N/A
Chemical Formula: C25H16FN3O3
Exact Mass: 425.1176
Molecular Weight: 425.42
Elemental Analysis: C, 70.58; H, 3.79; F, 4.47; N, 9.88; O, 11.28
The following data is based on the product molecular weight 425.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
