WF 2421 | CAS#128429-19-6 | inhibitor

MedKoo Cat#: 585410 | Name: WF 2421

Description:

WARNING: This product is for research use only, not for human or veterinary use.

WF 2421 is an aldose reductase inhibitor produced by Humicola grisea.

Chemical Structure

WF 2421

CAS#128429-19-6

Theoretical Analysis

MedKoo Cat#: 585410

Name: WF 2421

CAS#: 128429-19-6

Chemical Formula: C19H20N2O8

Exact Mass: 404.1220

Molecular Weight: 404.38

Elemental Analysis: C, 56.43; H, 4.99; N, 6.93; O, 31.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

WF 2421; WF2421; WF-2421

IUPAC/Chemical Name

2-formamido-3-[3-[5-(2-formamido-1-hydroxyethyl)-2-hydroxyphenyl]-4-hydroxyphenyl]-3-hydroxypropanoic acid

InChi Key

WQVWUCSBLUJLNT-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H20N2O8/c22-8-20-7-16(26)10-1-3-14(24)12(5-10)13-6-11(2-4-15(13)25)18(27)17(19(28)29)21-9-23/h1-6,8-9,16-18,24-27H,7H2,(H,20,22)(H,21,23)(H,28,29)

SMILES Code

O=C(O)C(NC=O)C(C1=CC=C(O)C(C2=CC(C(O)CNC=O)=CC=C2O)=C1)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 404.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Nishikawa M, Tsurumi Y, Murai H, Yoshida K, Okamoto M, Takase S, Tanaka H, Hirota H, Hashimoto M, Kohsaka M. WF-2421, a new aldose reductase inhibitor produced from a fungus, Humicola grisea. J Antibiot (Tokyo). 1991 Feb;44(2):130-5. PubMed PMID: 1901310.