TXS-8 | CAS# | MedKoo

MedKoo Cat#: 408064 | Name: TXS-8

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TXS-8 is Probe of Rpn-6, an Essential Subunit of the 26S Proteasome.

Chemical Structure

TXS-8

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 408064

Name: TXS-8

CAS#: N/A

Chemical Formula: C34H44N4O4

Exact Mass: 572.3363

Molecular Weight: 572.75

Elemental Analysis: C, 71.30; H, 7.74; N, 9.78; O, 11.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

TXS-8; TXS 8; TXS8;

IUPAC/Chemical Name

N-(2-amino-2-oxoethyl)-2-(N-(4-(tert-butyl)benzyl)-2-((2-ethoxybenzyl)amino)acetamido)-N-(2-methylbenzyl)acetamide

InChi Key

WHVMZAQYGTWVOX-UHFFFAOYSA-N

InChi Code

InChI=1S/C34H44N4O4/c1-6-42-30-14-10-9-12-27(30)19-36-20-32(40)37(21-26-15-17-29(18-16-26)34(3,4)5)24-33(41)38(23-31(35)39)22-28-13-8-7-11-25(28)2/h7-18,36H,6,19-24H2,1-5H3,(H2,35,39)

SMILES Code

NC(CN(CC1=CC=CC=C1C)C(CN(CC2=CC=C(C(C)(C)C)C=C2)C(CNCC3=CC=CC=C3OCC)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

A considerable number of essential cellular proteins have no catalytic activity and serve instead as structural components to aid in assembling protein complexes. For example, the assembly and function of the 26S proteasome, the major enzymatic complex necessary for ubiquitin-dependent protein degradation, require a number of essential protein contacts to associate the 19S regulatory particle with the 20S core particle.

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 572.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Discovery of a Small Molecule Probe of Rpn-6, an Essential Subunit of the 26S Proteasome Wenzhi TianDarci J. Trader* ACS Chemical Biology, Articles ASAP (Articles)Subscribed Access Publication Date (Web):December 26, 2019