MedKoo Cat#: 574208 | Name: α-hydroxy Metoprolol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

α-hydroxy Metoprolol is an active metabolite of the β1-adrenergic receptor blocker metoprolol. It is formed via metabolism of metoprolol by the cytochrome P450 (CYP) isoform CYP2D6.

Chemical Structure

α-hydroxy Metoprolol
α-hydroxy Metoprolol
CAS#56392-16-6

Theoretical Analysis

MedKoo Cat#: 574208

Name: α-hydroxy Metoprolol

CAS#: 56392-16-6

Chemical Formula: C15H25NO4

Exact Mass: 283.1784

Molecular Weight: 283.37

Elemental Analysis: C, 63.58; H, 8.89; N, 4.94; O, 22.58

Price and Availability

Size Price Availability Quantity
5mg USD 550.00 2 weeks
10mg USD 850.00 2 weeks
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Related CAS #
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Synonym
α-hydroxy Metoprolol
IUPAC/Chemical Name
4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-α-(methoxymethyl)-benzenemethanol
InChi Key
OFRYBPCSEMMZHR-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H25NO4/c1-11(2)16-8-13(17)9-20-14-6-4-12(5-7-14)15(18)10-19-3/h4-7,11,13,15-18H,8-10H2,1-3H3
SMILES Code
COCC(O)C1=CC=C(OCC(O)CNC(C)C)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 283.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Cerqueira, P.M., Cesarino, E.J., Bertucci, C., et al. Stereoselective metabolism of metoprolol: Enantioselectivity of α-hydroxymetoprolol in plasma and urine. Chirality 15(6), 542-549 (2003).