MedKoo Cat#: 558916 | Name: Cyanine3 DBCO
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azodibenzocyclooctyne (DBCO or ADIBO) is a stable but very reactive cycloalkyne for copper free Click chemistry. This reagent is a conjugate of DBCO with Cyanine3 fluorophore for the non-catalyzed, strain promoted reaction with azides.

Chemical Structure

Cyanine3 DBCO
Cyanine3 DBCO
CAS#2692677-79-3

Theoretical Analysis

MedKoo Cat#: 558916

Name: Cyanine3 DBCO

CAS#: 2692677-79-3

Chemical Formula: C51H57F6N4O2P

Exact Mass: 902.4123

Molecular Weight: 903.01

Elemental Analysis: C, 67.84; H, 6.36; F, 12.62; N, 6.20; O, 3.54; P, 3.43

Price and Availability

Size Price Availability Quantity
5mg USD 410.00 2 Weeks
10mg USD 750.00 2 Weeks
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Related CAS #
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Synonym
Cyanine3 DBCO; Cy3 DBCO;
IUPAC/Chemical Name
N-[6-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-6-oxohexyl]-6-[3,3-dimethyl-2-[3-(1,3,3-trimethylindol-1-ium-2-yl)prop-2-enylidene]indol-1-yl]hexanamide;hexafluorophosphate
InChi Key
PJPBLOHSDHYHJX-UHFFFAOYSA-O
InChi Code
InChI=1S/C51H56N4O2/c1-50(2)41-24-13-16-27-44(41)53(5)46(50)29-20-30-47-51(3,4)42-25-14-17-28-45(42)54(47)36-19-7-8-31-48(56)52-35-18-6-9-32-49(57)55-37-40-23-11-10-21-38(40)33-34-39-22-12-15-26-43(39)55/h10-17,20-30H,6-9,18-19,31-32,35-37H2,1-5H3/p+1
SMILES Code
CC1(C)C(/C=C/C=C2C(C)(C)C3=CC=CC=C3N\2C)=[N+](CCCCCC(NCCCCCC(N4C5=CC=CC=C5C#CC6=C(C=CC=C6)C4)=O)=O)C7=CC=CC=C71
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 903.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Cellular Uptake Evaluation of Amphiphilic Polymer Assemblies: Importance of Interplay between Pharmacological and Genetic Approaches. Biomacromolecules, 2019, 20(12), 4407–4418. doi: 10.1021/acs.biomac.9b01073