MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 582096 | Name: Decyl disulfide
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Decyl disulfide is a biochemical.

Chemical Structure

Decyl disulfide
Decyl disulfide
CAS#10496-18-1

Theoretical Analysis

MedKoo Cat#: 582096

Name: Decyl disulfide

CAS#: 10496-18-1

Chemical Formula: C20H42S2

Exact Mass: 346.2700

Molecular Weight: 346.68

Elemental Analysis: C, 69.29; H, 12.21; S, 18.50

Price and Availability

Size Price Availability Quantity
1g USD 250.00 2 Weeks
5g USD 450.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
1,2-Didecyldisulfane; Decyl disulfide; Didecyl Disulfide;
IUPAC/Chemical Name
1-(Decyldisulfanyl)decane
InChi Key
IDJPKRIELSFBPE-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H42S2/c1-3-5-7-9-11-13-15-17-19-21-22-20-18-16-14-12-10-8-6-4-2/h3-20H2,1-2H3
SMILES Code
S(SCCCCCCCCCC)CCCCCCCCCC
Appearance
Liquid
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 346.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li A, Zhang D. Synthesis and Characterization of Cleavable Core-Cross-Linked Micelles Based on Amphiphilic Block Copolypeptoids as Smart Drug Carriers. Biomacromolecules. 2016 Mar 14;17(3):852-61. doi: 10.1021/acs.biomac.5b01561. Epub 2016 Feb 26. PubMed PMID: 26866458. 2: Albayrak E, Karabuga S, Bracco G, Danışman MF. Investigation of the deposition and thermal behavior of striped phases of unsymmetric disulfide self-assembled monolayers on Au(111): the case of 11-hydroxyundecyl decyl disulfide. J Chem Phys. 2015 Jan 7;142(1):014703. doi: 10.1063/1.4903539. PubMed PMID: 25573574. 3: Wang H, Andersen KK, Sehgal P, Hagedorn J, Westh P, Borch K, Otzen DE. pH regulation of the kinetic stability of the lipase from Thermomyces lanuginosus. Biochemistry. 2013 Jan 8;52(1):264-76. doi: 10.1021/bi301258e. Epub 2012 Dec 26. PubMed PMID: 23249182. 4: Dou X, Menkari CE, Shanmugasundararaj S, Miller KW, Charness ME. Two alcohol binding residues interact across a domain interface of the L1 neural cell adhesion molecule and regulate cell adhesion. J Biol Chem. 2011 May 6;286(18):16131-9. doi: 10.1074/jbc.M110.209254. Epub 2011 Mar 2. PubMed PMID: 21367865; PubMed Central PMCID: PMC3091222. 5: Ochocki JD, Igbavboa U, Gibson Wood W, Wattenberg EV, Distefano MD. Enlarging the scope of cell-penetrating prenylated peptides to include farnesylated 'CAAX' box sequences and diverse cell types. Chem Biol Drug Des. 2010 Aug;76(2):107-15. doi: 10.1111/j.1747-0285.2010.00992.x. Epub 2010 Jun 23. PubMed PMID: 20584014; PubMed Central PMCID: PMC2919362. 6: Maeno K, Nakajima A, Conseil G, Rothnie A, Deeley RG, Cole SP. Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1). Drug Metab Dispos. 2009 Jul;37(7):1411-20. doi: 10.1124/dmd.109.026633. Epub 2009 Apr 27. PubMed PMID: 19398503. 7: Sachdeva S, Musayev F, Alhamadsheh MM, Neel Scarsdale J, Tonie Wright H, Reynolds KA. Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates. Bioorg Chem. 2008 Apr;36(2):85-90. Epub 2007 Dec 21. PubMed PMID: 18096200; PubMed Central PMCID: PMC2293971. 8: Chamani J. Comparison of the conformational stability of the non-native alpha-helical intermediate of thiol-modified beta-lactoglobulin upon interaction with sodium n-alkyl sulfates at two different pH. J Colloid Interface Sci. 2006 Jul 15;299(2):636-46. Epub 2006 Mar 3. PubMed PMID: 16554059. 9: Ashwell GJ, Mohib A. Improved molecular rectification from self-assembled monolayers of a sterically hindered dye. J Am Chem Soc. 2005 Nov 23;127(46):16238-44. PubMed PMID: 16287315. 10: Skulason H, Frisbie CD. Direct detection by atomic force microscopy of single bond forces associated with the rupture of discrete charge-transfer complexes. J Am Chem Soc. 2002 Dec 18;124(50):15125-33. PubMed PMID: 12475359. 11: Miura Y, Sasao Y, Dohi H, Nishida Y, Kobayashi K. Self-assembled monolayers of globotriaosylceramide (Gb3) mimics: surface-specific affinity with shiga toxins. Anal Biochem. 2002 Nov 1;310(1):27-35. PubMed PMID: 12413469. 12: Chabinyc ML, Chen X, Holmlin RE, Jacobs H, Skulason H, Frisbie CD, Mujica V, Ratner MA, Rampi MA, Whitesides GM. Molecular rectification in a metal-insulator-metal junction based on self-assembled monolayers. J Am Chem Soc. 2002 Oct 2;124(39):11730-6. PubMed PMID: 12296740. 13: Xie T, Yu L, Bader MW, Bardwell JC, Yu CA. Identification of the ubiquinone-binding domain in the disulfide catalyst disulfide bond protein B. J Biol Chem. 2002 Jan 18;277(3):1649-52. Epub 2001 Nov 6. PubMed PMID: 11698406. 14: Hagmann W, Nies AT, König J, Frey M, Zentgraf H, Keppler D. Purification of the human apical conjugate export pump MRP2 reconstitution and functional characterization as substrate-stimulated ATPase. Eur J Biochem. 1999 Oct 1;265(1):281-9. PubMed PMID: 10491184. 15: Carter BZ, Wiseman AL, Orkiszewski R, Ballard KD, Ou CN, Lieberman MW. Metabolism of leukotriene C4 in gamma-glutamyl transpeptidase-deficient mice. J Biol Chem. 1997 May 9;272(19):12305-10. PubMed PMID: 9139674. 16: Oblong JE, Chantler EL, Gallegos A, Kirkpatrick DL, Chen T, Marshall N, Powis G. Reversible inhibition of human thioredoxin reductase activity by cytotoxic alkyl 2-imidazolyl disulfide analogues. Cancer Chemother Pharmacol. 1994;34(5):434-8. PubMed PMID: 8070012. 17: Kirkpatrick DL. Kinetic study of the interaction of glutathione with four antitumor disulfides: possible mechanism for cellular glutathione depletion. Chem Biol Interact. 1989;69(2-3):225-34. PubMed PMID: 2702703. 18: Kirkpatrick DL. Modification of antitumor disulfide cytotoxicity by glutathione depletion in murine cells. Cancer Res. 1987 Aug 15;47(16):4391-5. PubMed PMID: 3607770. 19: Inomata M, Fukuoka F, Hoshi A, Kuretani K, Saneyoshi M. Antitumor activity of alkyldisulfide derivatives of 6 mercaptopurines against L-1210 leukemia. J Pharmacobiodyn. 1981 Dec;4(12):928-32. PubMed PMID: 7200518. 20: Inomata M, Fukuoka F, Hoshi A, Kuretani K, Saneyoshi M. Structure-antitumor activity relationship of purin-6-yl alkyl disulfides. J Pharmacobiodyn. 1981 Jan;4(1):58-64. PubMed PMID: 7196946.

View History

PDE1 inhibitor 1

PDE1 inhibitor 1