CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii. CAP 3 increases the fluidity of model Gram-negative bacterial membranes and binds to LPS in vitro. It reduces the biomass and number of colony-forming units in E. coli biofilms in a concentration-dependent manner. It is cytotoxic to A459 cells and has hemolytic activity against human red blood cells.
MedKoo Cat#: 574154
Name: CAP 3
CAS#: 2292123-03-4
Chemical Formula: C52H82N6O11
Exact Mass: 966.6042
Molecular Weight: 967.26
Elemental Analysis: C, 64.57; H, 8.55; N, 8.69; O, 18.19
The following data is based on the product molecular weight 967.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
