MedKoo Cat#: 558875 | Name: Sulfo-Cyanine5.5 carboxylic acid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfo-Cyanine5.5 (analog of Cy5.5®) is a water-soluble, far red emitting fluorophore. Due to four sulfo-groups, the dye possesses negative charge in neutral pH, and very high hydrophilicity. As a cyanine dye, sulfo-Cyanine5.5 shows very low dependence of the fluorescence on pH, and very high extinction coefficient.

Chemical Structure

Sulfo-Cyanine5.5 carboxylic acid
Sulfo-Cyanine5.5 carboxylic acid
CAS#2183440-68-6 (inner salt)

Theoretical Analysis

MedKoo Cat#: 558875

Name: Sulfo-Cyanine5.5 carboxylic acid

CAS#: 2183440-68-6 (inner salt)

Chemical Formula: C40H39K3N2O14S4

Exact Mass: 1016.0195

Molecular Weight: 1017.29

Elemental Analysis: C, 47.23; H, 3.86; K, 11.53; N, 2.75; O, 22.02; S, 12.61

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Synonym
Sulfo-Cyanine5.5 carboxylic acid
IUPAC/Chemical Name
potassium 3-(5-carboxypentyl)-1,1-dimethyl-2-((1E,3E,5E)-5-(1,1,3-trimethyl-6,8-disulfonato-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1H-benzo[e]indol-3-ium-6,8-disulfonate
InChi Key
MMQQUABRDYPOFX-UHFFFAOYSA-K
InChi Code
InChI=1S/C40H42N2O14S4.3K/c1-39(2)34(41(5)30-17-15-26-28(37(30)39)20-24(57(45,46)47)22-32(26)59(51,52)53)12-8-6-9-13-35-40(3,4)38-29-21-25(58(48,49)50)23-33(60(54,55)56)27(29)16-18-31(38)42(35)19-11-7-10-14-36(43)44;;;/h6,8-9,12-13,15-18,20-23H,7,10-11,14,19H2,1-5H3,(H4-,43,44,45,46,47,48,49,50,51,52,53,54,55,56);;;/q;3*+1/p-3
SMILES Code
CC(/C1=C\C=C\C=C\C2=[N+](CCCCCC(O)=O)C3=CC=C4C(C=C(S(=O)(O[K])=O)C=C4S(=O)([O-])=O)=C3C2(C)C)(C)C5=C6C(C(S(=O)(O[K])=O)=CC(S(=O)(O[K])=O)=C6)=CC=C5N1C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,017.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Wild, A.R.; Sinnen, B.L.; Dittmer, P.J.; Kennedy, M.J.; Sather, W.A.; Dell'Acqua, M.L. Synapse-to-Nucleus Communication through NFAT Is Mediated by L-type Ca2+ Channel Ca2+ Spike Propagation to the Soma. Cell Reports, 2019, 26, 3537–3550.e4. doi: 10.1016/j.celrep.2019.03.005