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MedKoo Cat#: 593161 | Name: CJ-887

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CJ-887 is a STAT3 inhibitor.

Chemical Structure

CJ-887
CJ-887
CAS#1220952-08-8

Theoretical Analysis

MedKoo Cat#: 593161

Name: CJ-887

CAS#: 1220952-08-8

Chemical Formula: C34H45N6O10P

Exact Mass: 728.2935

Molecular Weight: 728.74

Elemental Analysis: C, 56.04; H, 6.22; N, 11.53; O, 21.95; P, 4.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CJ887; CJ 887; CJ-887
IUPAC/Chemical Name
L-​Glutamamide, N-​acetyl-​O-​phosphono-​L-​tyrosyl-​(3S,​6S,​10aS)​-​6-​aminodecahydro-​5-​oxopyrrolo[1,​2-​a]​azocine-​3-​carbonyl-​N1-​(phenylmethyl)​-
InChi Key
MPMXKQWWMNFOFR-CISYKLKFSA-N
InChi Code
InChI=1S/C34H45N6O10P/c1-21(41)37-28(19-22-11-14-25(15-12-22)50-51(47,48)49)32(44)39-27-10-6-5-9-24-13-17-29(40(24)34(27)46)33(45)38-26(16-18-30(35)42)31(43)36-20-23-7-3-2-4-8-23/h2-4,7-8,11-12,14-15,24,26-29H,5-6,9-10,13,16-20H2,1H3,(H2,35,42)(H,36,43)(H,37,41)(H,38,45)(H,39,44)(H2,47,48,49)/t24-,26-,27-,28-,29-/m0/s1
SMILES Code
O=C([C@@H](NC(C)=O)CC1=CC=C(OP(O)(O)=O)C=C1)N[C@H]2CCCC[C@@H]3N([C@H](C(N[C@@H](CCC(N)=O)C(NCC4=CC=CC=C4)=O)=O)CC3)C2=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 728.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Fan, Y., Kong, R., Shen, J., & Tweardy, D. J. (Accepted/In press). Intrinsic molecular characteristics of inhibiting STAT3 activation and dimerization through targeting the phosphotyrosine binding site within the SH2 domain-A molecular dynamics study. Journal of Structural Biology. https://doi.org/10.1016/j.jsb.2013.02.005. (2019).