TYK2 JH2-IN-48 is a novel highly potent and selective TYK2 JH2 inhibitor, providing robust inhibition in a mouse IL-12-induced IFNγ pharmacodynamic model as well as efficacy in an IL-23 and IL-12-dependent mouse colitis model.
MedKoo Cat#: 533290
Name: TYK2 JH2-IN-48
CAS#: N/A
Chemical Formula: C18H15D3N6O3S
Exact Mass: 401.1349
Molecular Weight: 401.46
Elemental Analysis: C, 53.85; H, 5.27; N, 20.93; O, 11.96; S, 7.99
The following data is based on the product molecular weight 401.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
