MedKoo Cat#: 558842 | Name: TAMRA maleimide, 6-isomer
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TAMRA (aka TMR or tetramethylrhodamine) is a xanthene dye that has been used as a fluorescent label for decades. Xanthene dyes are available as two isomers (called 5- and 6-isomers) that have almost identical fluorescent properties, but need to be separated to avoid doubling and smearing of labeled product peaks or bands during chromatography or electrophoresis. This is a pure 6-isomer of TAMRA maleimide, used for the labeling of proteins and peptides via thiol (SH) groups

Chemical Structure

TAMRA maleimide, 6-isomer
TAMRA maleimide, 6-isomer
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 558842

Name: TAMRA maleimide, 6-isomer

CAS#: N/A

Chemical Formula: C31H28N4O6

Exact Mass: 552.2009

Molecular Weight: 552.59

Elemental Analysis: C, 67.38; H, 5.11; N, 10.14; O, 17.37

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Synonym
IUPAC/Chemical Name
3',6'-bis(dimethylamino)-N-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamide
InChi Key
LLYYNGSVFARFNI-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H28N4O6/c1-33(2)19-6-9-22-25(16-19)40-26-17-20(34(3)4)7-10-23(26)31(22)24-15-18(5-8-21(24)30(39)41-31)29(38)32-13-14-35-27(36)11-12-28(35)37/h5-12,15-17H,13-14H2,1-4H3,(H,32,38)
SMILES Code
CN(C)C1=CC=C2C(OC(C=C(N(C)C)C=C3)=C3C2(C4=CC(C(NCCN5C(C=CC5=O)=O)=O)=CC=C46)OC6=O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 552.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL