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MedKoo Cat#: 585302 | Name: UR 11353

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UR 11353 is a PAF antagonist that may be useful in treatment of some inflammatory skin diseases.

Chemical Structure

UR 11353
UR 11353
CAS#138060-13-6

Theoretical Analysis

MedKoo Cat#: 585302

Name: UR 11353

CAS#: 138060-13-6

Chemical Formula: C34H59ClN2O5

Exact Mass: 610.4113

Molecular Weight: 611.31

Elemental Analysis: C, 66.80; H, 9.73; Cl, 5.80; N, 4.58; O, 13.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
UR 11353; UR11353; UR-11353
IUPAC/Chemical Name
Pyridinium, 2-((acetyl(((tetrahydro5-(octadecyloxy)-3-furanyl)methoxy)carbonyl)amino)methyl)-1-ethyl, chloride
InChi Key
KFNNWINXWGVOQN-UHFFFAOYSA-M
InChi Code
InChI=1S/C34H59N2O5.ClH/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22-25-39-33-26-31(28-40-33)29-41-34(38)36(30(3)37)27-32-23-20-21-24-35(32)5-2;/h20-21,23-24,31,33H,4-19,22,25-29H2,1-3H3;1H/q+1;/p-1
SMILES Code
CC[N+]1=CC=CC=C1CN(C(C)=O)C(OCC2COC(OCCCCCCCCCCCCCCCCCC)C2)=O.[Cl-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 611.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Negro Alvarez JM, Miralles López JC, Ortiz Martínez JL, Abellán Alemán A, Rubio del Barrio R. Platelet-activating factor antagonists. Allergol Immunopathol (Madr). 1997 Sep-Oct;25(5):249-58. Review. PubMed PMID: 9395010. 2: Merlos M, Gómez LA, Giral M, Vericat ML, García-Rafanell J, Forn J. Effects of PAF-antagonists in mouse ear oedema induced by several inflammatory agents. Br J Pharmacol. 1991 Dec;104(4):990-4. PubMed PMID: 1810607; PubMed Central PMCID: PMC1908842. 3: Carceller E, Merlos M, Giral M, Bartrolí J, García-Rafanell J, Forn J. 4-substituted 2-alkoxytetrahydrofurans as potent and long-lasting PAF antagonists. J Med Chem. 1992 Feb 21;35(4):676-83. PubMed PMID: 1542094.