MedKoo Cat#: 582047 | Name: Dechloro trazodone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dechloro trazodone is an antipsychotic with potential use as a schizophrenia agent. Trazodone impurity B.

Chemical Structure

Dechloro trazodone
Dechloro trazodone
CAS#62337-66-0

Theoretical Analysis

MedKoo Cat#: 582047

Name: Dechloro trazodone

CAS#: 62337-66-0

Chemical Formula: C19H23N5O

Exact Mass: 337.1900

Molecular Weight: 337.43

Elemental Analysis: C, 67.63; H, 6.87; N, 20.76; O, 4.74

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Synonym
Dechloro trazodone; Deschloro trazodone; Trazodone hydrochloride impurity B; UNII-2Z5CF330GJ.
IUPAC/Chemical Name
2-(3-(4-Phenylpiperazin-1-yl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2H)-one
InChi Key
JGIRPKCVHRVHJZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H23N5O/c25-19-23-11-5-4-9-18(23)20-24(19)12-6-10-21-13-15-22(16-14-21)17-7-2-1-3-8-17/h1-5,7-9,11H,6,10,12-16H2
SMILES Code
O=C1N(CCCN2CCN(C3=CC=CC=C3)CC2)N=C4C=CC=CN41
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 337.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wen B, Ma L, Rodrigues AD, Zhu M. Detection of novel reactive metabolites of trazodone: evidence for CYP2D6-mediated bioactivation of m-chlorophenylpiperazine. Drug Metab Dispos. 2008 May;36(5):841-50. doi: 10.1124/dmd.107.019471. Epub 2008 Jan 31. PubMed PMID: 18238857.