MedKoo Cat#: 574119 | Name: Tyrosol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tyrosol is a fungicide that increases pulmonary superoxide dismutase (SOD) activity and decreases pulmonary macrophage and neutrophil infiltration, edema, inflammation, and myeloperoxidase (MPO) activity in acute lung injury. It reduces aqueous humor TNF-α, nitric oxide (NO), and prostaglandin E2 (PGE2) levels and cellular infiltration in a rat model of ocular endotoxin-induced uveitis (EIU). Tyrosol also decreases erythrocyte aggregation, increases the oxygen transport capacity index (OTCI), and abolishes cortical microvascular rarefaction in spontaneously hypertensive rats.

Chemical Structure

Tyrosol
Tyrosol
CAS#501-94-0

Theoretical Analysis

MedKoo Cat#: 574119

Name: Tyrosol

CAS#: 501-94-0

Chemical Formula: C8H10O2

Exact Mass: 138.0681

Molecular Weight: 138.17

Elemental Analysis: C, 69.55; H, 7.30; O, 23.16

Price and Availability

Size Price Availability Quantity
100g USD 255.00
250g USD 440.00
500g USD 675.00
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Related CAS #
No Data
Synonym
NSC 59876, p-HPEA, Tyrosol
IUPAC/Chemical Name
4-hydroxy-benzeneethanol
InChi Key
YCCILVSKPBXVIP-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H10O2/c9-6-5-7-1-3-8(10)4-2-7/h1-4,9-10H,5-6H2
SMILES Code
OC1=CC=C(CCO)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 138.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Roila R, Valiani A, Servili M, Ranucci D, Galarini R, Ortenzi R, Primavilla S, Branciari R. Control of Listeria monocytogenes on Frankfurters by Surface Treatment with Olive Mill Wastewater Polyphenolic Extract. Foods. 2025 Feb 24;14(5):774. doi: 10.3390/foods14050774. PMID: 40077477; PMCID: PMC11899662. 2: Del Coco L, Girelli CR, Gambacorta L, Solfrizzo M, Fanizzi FP. 1H NMR Spectroscopy Primitivo Red Wine Screening After Grape Pomace Repassage for Possible Toxin Contamination Removal. Foods. 2025 Feb 21;14(5):734. doi: 10.3390/foods14050734. PMID: 40077432; PMCID: PMC11898919. 3: Song N, Xia H, Yang X, Liu S, Xu L, Zhuang K, Yao L, Yang S, Chen X, Dai J. Transcriptome analysis and reverse engineering verification of SNZ3Val125Ile and Pho3Asn134Asp revealed the mechanism of adaptive laboratory evolution to increase the yield of tyrosol in Saccharomyces cerevisiae strain S26-AE2. Biotechnol Biofuels Bioprod. 2025 Mar 5;18(1):29. doi: 10.1186/s13068-025-02627-4. PMID: 40045317; PMCID: PMC11884060. 4: Ji L, Shi Q, Shangguan Y, Chen C, Zhu J, Dong Z, Hong X, Liu X, Wei C, Zhu X, Li W. Molecular Response and Metabolic Reprogramming of the Spleen Coping with Cold Stress in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis). Antioxidants (Basel). 2025 Feb 14;14(2):217. doi: 10.3390/antiox14020217. PMID: 40002403; PMCID: PMC11852077. 5: Wang Y, Zhang Y, Li S, Huang K, Cao H, Qiu W, Guan X. Mechanism of the release and transformation of polyphenols during germination and fermentation in millets: profile and metabolomics based analysis. Food Funct. 2025 Mar 3;16(5):2004-2017. doi: 10.1039/d4fo05625f. PMID: 39960291. 6: Koprivnjak O, Majetić Germek V, Žurga P, Brkić Bubola K. The Influence of Standard and Freeze-Dried Tofu on the Phenols and Quality of Virgin Olive Oil Used as an Immersion Medium. Molecules. 2025 Feb 3;30(3):672. doi: 10.3390/molecules30030672. PMID: 39942776; PMCID: PMC11821093. 7: Niwa T, Kato Y, Osawa T. In Vitro Anti-inflammatory Activity of Tyrosol and Tryptophol: Metabolites of Yeast via the Ehrlich Pathway. Biol Pharm Bull. 2025;48(2):115-118. doi: 10.1248/bpb.b24-00625. PMID: 39938894. 8: Qing L, Qian X, Zhu H, Wang J, Sun J, Jin Z, Tang X, Zhao Y, Wang G, Zhao J, Chen W, Tian P. Maternal-infant probiotic transmission mitigates early-life stress-induced autism in mice. Gut Microbes. 2025 Dec;17(1):2456584. doi: 10.1080/19490976.2025.2456584. Epub 2025 Feb 11. PMID: 39931863; PMCID: PMC11817528. 9: Hirasawa T, Satoh Y, Koma D. Production of aromatic amino acids and their derivatives by Escherichia coli and Corynebacterium glutamicum. World J Microbiol Biotechnol. 2025 Feb 7;41(2):65. doi: 10.1007/s11274-025-04264-3. PMID: 39915353; PMCID: PMC11802643. 10: Ma R, Huang Z, Jiang Y, Zhao A, Yu G, Lin C, Zhu L, Zhang X, Li X, Wang C. Regulation of ethanol production from anaerobic fermentation of food waste using aromatic alcohol-based quorum-sensing molecules. J Environ Manage. 2025 Mar;376:124382. doi: 10.1016/j.jenvman.2025.124382. Epub 2025 Feb 5. PMID: 39914213. 11: You L, Zhao W, Li X, Yang C, Guo P. Tyrosol protects RPE cells from H2O2-induced oxidative damage in vitro and in vivo through activation of the Nrf2/HO-1 pathway. Eur J Pharmacol. 2025 Mar 15;991:177316. doi: 10.1016/j.ejphar.2025.177316. Epub 2025 Jan 29. PMID: 39890008. 12: Zhou XL, Zhang MS, Zheng XR, Zhang ZQ, Liu JZ. Increasing the robustness of Escherichia coli for aromatic chemicals production through transcription factor engineering. Adv Biotechnol (Singap). 2024 Apr 2;2(2):15. doi: 10.1007/s44307-024-00023-x. PMID: 39883341; PMCID: PMC11740835. 13: Černáková L, Haluz P, Mastihuba V, Košťálová Z, Karnišová Potocká E, Mastihubová M. Enzymatic β-Mannosylation of Phenylethanoid Alcohols. Molecules. 2025 Jan 19;30(2):414. doi: 10.3390/molecules30020414. PMID: 39860283; PMCID: PMC11767590. 14: Mehany T, González-Sáiz JM, Pizarro C. Improving the Biostability of Extra Virgin Olive Oil with Olive Fruit Extract During Prolonged Deep Frying. Foods. 2025 Jan 15;14(2):260. doi: 10.3390/foods14020260. PMID: 39856925; PMCID: PMC11765049. 15: Huang W, Yan Y, Tian W, Cui X, Wang Y, Song Y, Mo T, Xu X, Zhao S, Liu Y, Wang X, Wang J, Jiang Y, Li J, Shi SP, Liu X, Tu P. Complete pathway elucidation of echinacoside in Cistanche tubulosa and de novo biosynthesis of phenylethanoid glycosides. Nat Commun. 2025 Jan 21;16(1):882. doi: 10.1038/s41467-025-56243-9. PMID: 39837891; PMCID: PMC11751479. 16: Frumuzachi O, Kieserling H, Rohn S, Mocan A. The impact of oleuropein, hydroxytyrosol, and tyrosol on cardiometabolic risk factors: a meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2025 Jan 19:1-21. doi: 10.1080/10408398.2025.2453090. Epub ahead of print. PMID: 39828996. 17: Bayer IS. Fungal quorum sensing molecules as potential drugs in the treatment of chronic wounds and their delivery. Expert Opin Drug Deliv. 2025 Feb;22(2):277-296. doi: 10.1080/17425247.2025.2452303. Epub 2025 Jan 15. PMID: 39791701. 18: Fierri I, Chignola R, Stranieri C, Di Leo EG, Bellumori M, Roncoletta S, Romeo A, Benetti F, Fratta Pasini AM, Zoccatelli G. Formulation, Characterization, and Antioxidant Properties of Chitosan Nanoparticles Containing Phenolic Compounds from Olive Pomace. Antioxidants (Basel). 2024 Dec 12;13(12):1522. doi: 10.3390/antiox13121522. PMID: 39765850; PMCID: PMC11726745. 19: Liu WK, Ren XX, Xu L, Lin J. Modular cascade with engineered HpaB for efficient synthesis of hydroxytyrosol. Bioorg Chem. 2025 Feb;155:108125. doi: 10.1016/j.bioorg.2025.108125. Epub 2025 Jan 3. PMID: 39764921. 20: Salvatore MM, Maione A, Buonanno A, Guida M, Andolfi A, Salvatore F, Galdiero E. Biological activities, biosynthetic capacity and metabolic interactions of lactic acid bacteria and yeast strains from traditional home- made kefir. Food Chem. 2025 Apr 1;470:142657. doi: 10.1016/j.foodchem.2024.142657. Epub 2024 Dec 31. PMID: 39756085.