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MedKoo Cat#: 574113 | Name: Erythromycylamine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Erythromycylamine is a macrolide antibiotic and an active metabolite of dirithromycin. It is active against a variety of bacteria, including strains of S. pyogenes, S. pneumoniae, L. monocytogenes, and B. pertussis. It is also active against 28 clinical isolates of M. avium complex (MAC) isolated from patients with AIDS. Erythromycylamine inhibits polylysine and polyproline synthesis in a cell-free assay.

Chemical Structure

Erythromycylamine
Erythromycylamine
CAS#26116-56-3

Theoretical Analysis

MedKoo Cat#: 574113

Name: Erythromycylamine

CAS#: 26116-56-3

Chemical Formula: C37H70N2O12

Exact Mass: 734.4929

Molecular Weight: 734.97

Elemental Analysis: C, 60.47; H, 9.60; N, 3.81; O, 26.12

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
Erythromycylamine; 9(S)-Erythromycylamine; 9-Epierythromycylamine; (9S)-erythromycyclamine; (9S)-9-Amino-9-deoxoerythromycin; BRL 42852ER; LY024410; LY 024410; LY-024410
IUPAC/Chemical Name
(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
InChi Key
XCLJRCAJSCMIND-JCTYMORFSA-N
InChi Code
InChI=1S/C37H70N2O12/c1-14-25-37(10,45)30(41)20(4)27(38)18(2)16-35(8,44)32(51-34-28(40)24(39(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-32,34,40-42,44-45H,14-17,38H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,27+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
SMILES Code
C[C@H]1[C@H](O)[C@@](OC)(C)C[C@@](O[C@H]([C@H]2C)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@](C)(O)C[C@@H](C)[C@H](N)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC2=O)([H])O1
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 734.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Hardy, D.J., Hensey, D.M., Beyer, J.M., et al. Comparative in vitro activities of new 14-, 15-, and 16-membered macrolides. Antimicrob. Agents Chemother. 32(11), 1710-1719 (1988). 2. Naik, S., and Ruck, R. In vitro activities of several new macrolide antibiotics against Mycobacterium avium complex. Antimicrob. Agents Chemother. 33(9), 1614-1616 (1989). 3. Matijašević, P., Franjić, N., Đokić, S., et al. Erythromycin series. X. Inhibitory activity of several new erythromycin derivatives in cell-free amino acid polymerization systems. Croat. Chem. Acta 53(3), 519-524 (1980).