Ribitol is a pentose sugar alcohol derived from ribose in vivo via the pentose phosphate pathway. It is a component of the glycopolymer teichoic acid in bacterial cell walls. Levels of ribitol are increased in the brain, cerebrospinal fluid, urine, and plasma of a patient with ribose-5-phosphate isomerase (RPI) deficiency, an extremely rare inborn error of metabolism characterized by a heterozygous frameshift mutation and missense allele in the RPI gene leading to leukoencephalopathy and mild peripheral polyneuropathy.
MedKoo Cat#: 574104
Name: Ribitol
CAS#: 488-81-3
Chemical Formula: C5H12O5
Exact Mass: 152.0685
Molecular Weight: 152.15
Elemental Analysis: C, 39.47; H, 7.95; O, 52.58
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.3 | 216.06 | |
| Water | 100.0 | 657.25 |
The following data is based on the product molecular weight 152.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
