MedKoo Cat#: 574098 | Name: YW1159
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

YW1159 is an inhibitor of Wnt signaling.

Chemical Structure

YW1159
YW1159
CAS#2131223-69-1

Theoretical Analysis

MedKoo Cat#: 574098

Name: YW1159

CAS#: 2131223-69-1

Chemical Formula: C19H14FN5O

Exact Mass: 347.1182

Molecular Weight: 347.35

Elemental Analysis: C, 65.70; H, 4.06; F, 5.47; N, 20.16; O, 4.61

Price and Availability

Size Price Availability Quantity
1mg USD 230.00
5mg USD 525.00
10mg USD 895.00
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Related CAS #
No Data
Synonym
Compound 3d, YW1159, YW 1159, YW-1159
IUPAC/Chemical Name
1-(2-fluorophenyl)-5-methyl-N-2-quinolinyl-1H-1,2,3-triazole-4-carboxamide
InChi Key
PNGUNLPOXKPCPK-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H14FN5O/c1-12-18(23-24-25(12)16-9-5-3-7-14(16)20)19(26)22-17-11-10-13-6-2-4-8-15(13)21-17/h2-11H,1H3,(H,21,22,26)
SMILES Code
O=C(C1=C(C)N(C2=C(F)C=CC=C2)N=N1)NC3=CC=C(C=CC=C4)C4=N3
Appearance
A crystalline solid
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
λmax: 257, 318, 332 nm

Preparing Stock Solutions

The following data is based on the product molecular weight 347.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Xue, F., and Shu, Y. Wnt signaling pathway inhibitors for treatments of disease. WO 2017/151786 Al, (2017). 2. Obianom, O.N., Ai, Y., Li, Y., et al. Triazole-based inhibitors of the Wnt/β-catenin signaling pathway improve glucose and lipid metabolism in diet-induced obese mice. J. Med. Chem. 62(2), 727-741 (2019).