TMCB is a dual inhibitor of casein kinase 2 (CK2) and ERK8. It also binds to Pim-1, HIPK2, and DYRK1A. TMCB induces apoptosis in Jurkat cells when used at concentrations ranging from 10 to 50 µM.
MedKoo Cat#: 574092
Name: TMCB
CAS#: 1085822-09-8
Chemical Formula: C11H9Br4N3O2
Exact Mass: 530.7428
Molecular Weight: 534.83
Elemental Analysis: C, 24.70; H, 1.70; Br, 59.76; N, 7.86; O, 5.98
The following data is based on the product molecular weight 534.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
