EN6 is a novel covalent autophagy activator targeting cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase which activates mTORC1 via the Rag guanosine triphosphatases.
MedKoo Cat#: 533175
Name: EN6
CAS#: 1808714-73-9
Chemical Formula: C19H14F2N4O2
Exact Mass: 368.1085
Molecular Weight: 368.34
Elemental Analysis: C, 61.96; H, 3.83; F, 10.32; N, 15.21; O, 8.69
The following data is based on the product molecular weight 368.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
