TA 7552 | CAS#104756-72-1 | hypocholesterolemic

MedKoo Cat#: 585263 | Name: TA 7552

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TA 7552 is a hypocholesterolemic agent.

Chemical Structure

TA 7552

CAS#104756-72-1

Theoretical Analysis

MedKoo Cat#: 585263

Name: TA 7552

CAS#: 104756-72-1

Chemical Formula: C25H26O10

Exact Mass: 486.1526

Molecular Weight: 486.47

Elemental Analysis: C, 61.72; H, 5.39; O, 32.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

TA 7552; TA7552; TA-7552

IUPAC/Chemical Name

2,3-Naphthalenedicarboxylic acid, 4-(3,4-dimethoxyphenyl)-1-hydroxy-5,6,7-trimethoxy-, dimethyl ester

InChi Key

DTCYXOLBEPGOHV-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H26O10/c1-29-14-9-8-12(10-15(14)30-2)17-18-13(11-16(31-3)22(32-4)23(18)33-5)21(26)20(25(28)35-7)19(17)24(27)34-6/h8-11,26H,1-7H3

SMILES Code

O=C(C1=C(C(OC)=O)C(C2=CC=C(OC)C(OC)=C2)=C3C(OC)=C(OC)C(OC)=CC3=C1O)OC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 486.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Takashima K, Kohno T, Mori T, Ohtani A, Hirakoso K, Takeyama S. The hypocholesterolemic action of TA-7552 and its effects on cholesterol metabolism in the rat. Atherosclerosis. 1994 Jun;107(2):247-57. PubMed PMID: 7980699. 2: Kubo H, Osawa T, Takashima K, Mizobe M. Enhancement of oral bioavailability and pharmacological effect of 1-(3,4-dimethoxyphenyl)-2,3-bis(methoxycarbonyl)-4-hydroxy-6,7,8- trimethoxynaphthalene (TA-7552), a new hypocholesterolemic agent, by micronization in co-ground mixture with D-mannitol. Biol Pharm Bull. 1996 May;19(5):741-7. PubMed PMID: 8741587. 3: Iwasaki T, Kondo K, Nishitani T, Kuroda T, Hirakoso K, Ohtani A, Takashima K. Arylnaphthalene lignans as novel series of hypolipidemic agents raising high-density lipoprotein level. Chem Pharm Bull (Tokyo). 1995 Oct;43(10):1701-5. PubMed PMID: 8536344.