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MedKoo Cat#: 593132 | Name: LUF5771

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LUF5771 is an allosteric inhibitor of the luteinizing hormone receptor.

Chemical Structure

LUF5771
LUF5771
CAS#1141802-49-4

Theoretical Analysis

MedKoo Cat#: 593132

Name: LUF5771

CAS#: 1141802-49-4

Chemical Formula: C24H23NO

Exact Mass: 357.1729

Molecular Weight: 357.45

Elemental Analysis: C, 80.64; H, 6.49; N, 3.92; O, 8.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LUF5771; LUF 5771; LUF-5771
IUPAC/Chemical Name
[1,1':3',1''-Terphenyl]-5'-yl N-cyclopentylcarbamate
InChi Key
YNYOWRRXJIPCGX-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H23NO2/c26-24(25-22-13-7-8-14-22)27-23-16-20(18-9-3-1-4-10-18)15-21(17-23)19-11-5-2-6-12-19/h1-6,9-12,15-17,22H,7-8,13-14H2,(H,25,26)
SMILES Code
O=C(OC1=CC(C2=CC=CC=C2)=CC(C3=CC=CC=C3)=C1)NC4CCCC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 100.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 357.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Luo QL, Tan JP, Li ZF, Nan WH, Xiao DR. Suzuki-Miyaura coupling of aryl iodides, bromides, and chlorides catalyzed by bis(thiazole) pincer palladium complexes. J Org Chem. 2012 Sep 21;77(18):8332-7. Epub 2012 Sep 7. PubMed PMID: 22928706. 2: Heitman LH, Kleinau G, Brussee J, Krause G, Ijzerman AP. Determination of different putative allosteric binding pockets at the lutropin receptor by using diverse drug-like low molecular weight ligands. Mol Cell Endocrinol. 2012 Apr 4;351(2):326-36. doi: 10.1016/j.mce.2012.01.010. Epub 2012 Jan 18. PubMed PMID: 22269095. 3: Heitman LH, Narlawar R, de Vries H, Willemsen MN, Wolfram D, Brussee J, Ijzerman AP. Substituted terphenyl compounds as the first class of low molecular weight allosteric inhibitors of the luteinizing hormone receptor. J Med Chem. 2009 Apr 9;52(7):2036-42. doi: 10.1021/jm801561h. Erratum in: J Med Chem. 2010 Jan 14;53(1):520. PubMed PMID: 19296599.

View History

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