MedKoo Cat#: 582022 | Name: sec-Butylamine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

sec-Butylamine, (+/-)-2-Aminobutane is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

Chemical Structure

sec-Butylamine
sec-Butylamine
CAS#13952-84-6

Theoretical Analysis

MedKoo Cat#: 582022

Name: sec-Butylamine

CAS#: 13952-84-6

Chemical Formula: C4H11N

Exact Mass: 73.0900

Molecular Weight: 73.14

Elemental Analysis: C, 65.69; H, 15.16; N, 19.15

Price and Availability

Size Price Availability Quantity
5g USD 190.00
25g USD 310.00
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Synonym
sec-Butylamine; 1-Methylpropylamine; 2-Aminobutane; Butafume; Butylamine; Deccotane; Frucote; Tutane; Propylamine, 1-methyl.
IUPAC/Chemical Name
(R)-butan-2-amine
InChi Key
BHRZNVHARXXAHW-SCSAIBSYSA-N
InChi Code
InChI=1S/C4H11N/c1-3-4(2)5/h4H,3,5H2,1-2H3/t4-/m1/s1
SMILES Code
C([C@@H](C)N)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 73.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nardini V, Palaretti V, Dias LG, da Silva GVJ. An Explanation about the Use of (S)-Citronellal as a Chiral Derivatizing Agent (CDA) in (1)H and (13)C NMR for Sec-Butylamine, Methylbenzylamine, and Amphetamine: A Theoretical-Experimental Study. Molecules. 2019 Aug 3;24(15). pii: E2830. doi: 10.3390/molecules24152830. PubMed PMID: 31382590; PubMed Central PMCID: PMC6695982. 2: Douša M. Enantioseparation of N-acetyl-dl-cysteine as o-phtaldialdehyde derivatives obtained with various primary aliphatic amine additives on polysaccharide-based chiral stationary phases. J Pharm Biomed Anal. 2019 Mar 20;166:147-154. doi: 10.1016/j.jpba.2019.01.006. Epub 2019 Jan 8. PubMed PMID: 30640045. 3: Nie XL, Wang H, Zou J. [Synthesis of particle-free silver conductive ink and investigation of fabrication of conductive film by printing]. Guang Pu Xue Yu Guang Pu Fen Xi. 2012 Nov;32(11):3089-92. Chinese. PubMed PMID: 23387185. 4: Mal SS, Stephens FH, Baker RT. Transition metal catalysed dehydrogenation of amine-borane fuel blends. Chem Commun (Camb). 2011 Mar 14;47(10):2922-4. doi: 10.1039/c0cc03585h. Epub 2011 Jan 24. PubMed PMID: 21258748. 5: Masek V, Anzenbacherová E, Machová M, Brabec V, Anzenbacher P. Interaction of antitumor platinum complexes with human liver microsomal cytochromes P450. Anticancer Drugs. 2009 Jun;20(5):305-11. PubMed PMID: 19378397. 6: Canepari S, Carunchio V, Castellano P, Messina A. Protonation and silver(I) complex-formation equilibria of some amino-alcohols. Talanta. 1997 Nov;44(11):2059-67. PubMed PMID: 18966953. 7: Letzel MC, Schäfer C, Novara FR, Speranza M, Rozhenko AB, Schoeller WW, Mattay J. A kinetic study of guest displacement reactions on a host-guest complex with a photoswitchable calixarene. J Mass Spectrom. 2008 Nov;43(11):1553-64. doi: 10.1002/jms.1464. PubMed PMID: 18698554. 8: Wang SM, Dou GF, Li Q, Liu T, Meng ZY, Lou YQ, Zhang GL. Pharmacokinetics and metabolism of 3,4-dichlorophenyl-propenoyl-sec.-butylamine in rats by high performance liquid chromatography-ion trap mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):92-100. Epub 2006 Dec 1. PubMed PMID: 17141584. 9: Iwaki H, Shimizu M, Tokuyama T, Hasegawa Y. Purification and characterization of a novel cyclohexylamine oxidase from the cyclohexylamine-degrading Brevibacterium oxydans IH-35A. J Biosci Bioeng. 1999;88(3):264-8. PubMed PMID: 16232609. 10: Iwasaki A, Yamada Y, Kizaki N, Ikenaka Y, Hasegawa J. Microbial synthesis of chiral amines by (R)-specific transamination with Arthrobacter sp. KNK168. Appl Microbiol Biotechnol. 2006 Jan;69(5):499-505. Epub 2005 Jul 8. PubMed PMID: 16003558. 11: Witt M, Kreft D, Grützmacher HF. Elementary supramolecular chemistry in the gas phase: ligand exchange reactions of proton-bound clusters of aliphatic amides and diamides with amines. Phys Chem Chem Phys. 2005 Mar 7;7(5):1065-72. PubMed PMID: 19791400. 12: Calabro G, Drommi D, Bruno G, Faraone F. Effect of chelating vs. bridging coordination of chiral short-bite P-X-P (X=C, N, O) ligands in enantioselective palladium-catalysed allylic substitution reactions. Dalton Trans. 2004 Jan 7;(1):81-9. Epub 2003 Nov 14. PubMed PMID: 15356745. 13: Yun H, Cho BK, Kim BG. Kinetic resolution of (R,S)-sec-butylamine using omega-transaminase from Vibrio fluvialis JS17 under reduced pressure. Biotechnol Bioeng. 2004 Sep 20;87(6):772-8. PubMed PMID: 15329935. 14: Prokop R, Kasparkova J, Novakova O, Marini V, Pizarro AM, Navarro-Ranninger C, Brabec V. DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand. Biochem Pharmacol. 2004 Mar 15;67(6):1097-109. PubMed PMID: 15006546. 15: Iwasaki A, Yamada Y, Ikenaka Y, Hasegawa J. Microbial synthesis of (R)- and (S)-3,4-dimethoxyamphetamines through stereoselective transamination. Biotechnol Lett. 2003 Nov;25(21):1843-6. PubMed PMID: 14677709. 16: Moon D, Lah MS, Del Sesto RE, Miller JS. The effect of ligand charge on the coordination geometry of an Fe(III)ion: five- and six-coordinate Fe(III) complexes of tris(2-benzimidazolylmethyl)amine. Inorg Chem. 2002 Sep 9;41(18):4708-14. PubMed PMID: 12206694. 17: Shin JS, Kim BG. Comparison of the omega-transaminases from different microorganisms and application to production of chiral amines. Biosci Biotechnol Biochem. 2001 Aug;65(8):1782-8. PubMed PMID: 11577718. 18: Tzatzarakis M, Tsatsakis AM, Liakou A, Vakalounakis DJ. Effect of common food preservatives on mycelial growth and spore germination of Fusarium oxysporum. J Environ Sci Health B. 2000 Jul;35(4):527-37. PubMed PMID: 10874628. 19: Zhou Y, Shao G, Mou S. [Study on ion chromatography (IC) for the low-molecular weight amines]. Se Pu. 1997 May;15(3):243-5. Chinese. PubMed PMID: 15739369. 20: Gündüz T, Kiliç E, Cakirer O. Thermometric titrations of amines with nitrosyl perchlorate in acetonitrile solvent. Talanta. 1996 May;43(5):771-6. PubMed PMID: 18966547.