AM-12 is a TRPC5 inhibitor and Galangin derivative that inhibits effects of TRPC5 activator (-)-Englerin A but potentiates effects of physiological activators Sphingosine-1-phosphate and LPC.
MedKoo Cat#: 574077
Name: AM-12
CAS#: 2387510-84-9
Chemical Formula: C15H9BrO5
Exact Mass: 347.9633
Molecular Weight: 349.14
Elemental Analysis: C, 51.60; H, 2.60; Br, 22.89; O, 22.91
The following data is based on the product molecular weight 349.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
