CCW 28-3 is a novel potent covalent BRD4 degrader, degrading BRD4 in a proteasome- and RNF4-dependent manner without inhibiting RNF4 autoubiquitination activity.
MedKoo Cat#: 533158
Name: CCW 28-3
CAS#: 2361142-23-4
Chemical Formula: C44H42Cl2N6O4S
Exact Mass: 820.2365
Molecular Weight: 821.82
Elemental Analysis: C, 64.31; H, 5.15; Cl, 8.63; N, 10.23; O, 7.79; S, 3.90
The following data is based on the product molecular weight 821.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
