MedKoo Cat#: 558790 | Name: Sulfo-Cyanine7 NHS ester
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfo-Cyanine7 is an improved analog of Cy7 fluorophore with higher quantum yield and photostability. This fluorescent dye is especially useful for NIR imaging. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and drug design related experiments.

Chemical Structure

Sulfo-Cyanine7 NHS ester
Sulfo-Cyanine7 NHS ester
CAS#1603861-95-5 (potassium salt)

Theoretical Analysis

MedKoo Cat#: 558790

Name: Sulfo-Cyanine7 NHS ester

CAS#: 1603861-95-5 (potassium salt)

Chemical Formula: C41H46KN3O10S

Exact Mass: 843.2300

Molecular Weight: 844.05

Elemental Analysis: C, 58.34; H, 5.49; K, 4.63; N, 4.98; O, 18.96; S, 7.60

Price and Availability

Size Price Availability Quantity
5mg USD 470.00
25mg USD 980.00
50mg USD 1,720.00
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Related CAS #
1604244-45-2 (inner salt)
Synonym
Sulfo-Cyanine 7 NHS ester,SulfoCyanine7 NHS ester, SulfoCyanine 7 NHS ester, Sulfo-Cy7 NHS ester,SulfoCy7 NHS ester
IUPAC/Chemical Name
potassium 1-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-3,3-dimethyl-2-((E)-2-((E)-3-(2-((E)-1,3,3-trimethyl-5-sulfonatoindolin-2-ylidene)ethylidene)cyclohex-1-en-1-yl)vinyl)-3H-indol-1-ium-5-sulfonate
InChi Key
CURNAWIXNAMTKN-UHFFFAOYSA-M
InChi Code
InChI=1S/C41H47N3O10S2.K/c1-40(2)31-25-29(55(48,49)50)15-17-33(31)42(5)35(40)19-13-27-10-9-11-28(24-27)14-20-36-41(3,4)32-26-30(56(51,52)53)16-18-34(32)43(36)23-8-6-7-12-39(47)54-44-37(45)21-22-38(44)46;/h13-20,24-26H,6-12,21-23H2,1-5H3,(H-,48,49,50,51,52,53);/q;+1/p-1
SMILES Code
CC1(C)C(/C=C/C2=C/C(CCC2)=C/C=C3N(C)C4=CC=C(S(=O)(O[K])=O)C=C4C/3(C)C)=[N+](CCCCCC(ON5C(CCC5=O)=O)=O)C6=CC=C(S(=O)([O-])=O)C=C61
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 844.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Anani, T.; Brannen, A.; Panizzi, P.; Duin, E.C.; David, A.E. Quantitative, real-time in vivo tracking of magnetic nanoparticles using multispectral optoacoustic tomography (MSOT) imaging. Journal of Pharmaceutical and Biomedical Analysis, in press. doi: 10.1016/j.jpba.2019.112951 2. Katsumata, K.; Ishihara, J.; Mansurov, A.; Ishihara, A.; Raczy, M.M.; Yuba, E.; Hubbell, J.A. Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies. Science Advances, 2019, 5(11), eaay1971. doi: 10.1126/sciadv.aay1971 3. Mazur, C.; Powers, B.; Zasadny, K.; Sullivan, J.M.; Dimant, H.; Kamme, F.; Hesterman, J.; Matson, J.; Oestergaard, M.; Seaman, M.; Holt, R.W.; Qutaish, M.; Polyak, I.; Coelho, R.; Gottumukkala, V.; Gaut, C.M.; Berridge, M.; Albargothy, N.J.; Kelly, L.; Carare, R.O.; Hoppin, J.; Kordasiewicz, H.; Swayze, E.E.; Verma, A. Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging. JCI Insight, 2019, 4(20), 129240. doi: 10.1172/jci.insight.129240 4. Bykov, Y.; Cohen, N.; Gabrielli, N.; Manenschijn, H.; Welsch, S.; Chlanda, P.; Kukulski, W.; Patil, K.R.R.; Schuldiner, M.; Briggs, J.A.G. High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding. Journal of Cell Biology, 2019, 218(8), 2797–2811. doi: 10.1083/jcb.201812081