SYN-2903 | CAS#210563-03-4 | antifungal

MedKoo Cat#: 585231 | Name: SYN-2903

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SYN-2903 is a derivative of the triazole antifungal agent SYN-2869.

Chemical Structure

SYN-2903

CAS#210563-03-4

Theoretical Analysis

MedKoo Cat#: 585231

Name: SYN-2903

CAS#: 210563-03-4

Chemical Formula: C32H30F6N8O2

Exact Mass: 672.2396

Molecular Weight: 672.64

Elemental Analysis: C, 57.14; H, 4.50; F, 16.95; N, 16.66; O, 4.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

SYN-2903; SYN2903; SYN 2903

IUPAC/Chemical Name

3H-1,2,4-Triazol-3-one, 4-(4-(4-((1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl)-1-piperazinyl)-3-fluorophenyl)-2,4-dihydro-2-((4-(trifluoromethyl)phenyl)methyl)-

InChi Key

PCYZZKYRNGSDMF-ROTAYESASA-N

InChi Code

InChI=1S/C32H30F6N8O2/c1-21(31(48,17-44-19-39-18-40-44)26-8-6-24(33)14-27(26)34)42-10-12-43(13-11-42)29-9-7-25(15-28(29)35)45-20-41-46(30(45)47)16-22-2-4-23(5-3-22)32(36,37)38/h2-9,14-15,18-21,48H,10-13,16-17H2,1H3/t21-,31-/m1/s1

SMILES Code

O=C1N(CC2=CC=C(C(F)(F)F)C=C2)N=CN1C3=CC=C(N4CCN([C@H](C)[C@@](O)(C5=CC=C(F)C=C5F)CN6N=CN=C6)CC4)C(F)=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 672.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Khan JK, Montaseri H, Poglod M, Bu HZ, Zuo Z, Salama SM, Daneshtalab M, Micetich RG. Interspecies comparison of pharmacokinetics of the novel triazole antifungal agent SYN-2869 and its derivatives. Antimicrob Agents Chemother. 2000 Apr;44(4):910-5. PubMed PMID: 10722490; PubMed Central PMCID: PMC89791. 2: Bu HZ, Khan JK, Poglod M, Micetich RG. Liquid chromatographic-electrospray tandem mass spectrometric determination of novel antifungal agents in plasma. J Chromatogr B Biomed Sci Appl. 1999 Mar 19;724(2):311-7. PubMed PMID: 10219673.