MedKoo Cat#: 558787 | Name: ROX NHS ester, 5-isomer
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

This product is a derivative of pure 5-carboxy-ROX.5-Carboxy-X-rhodamine N-succinimidyl ester (ROX-SE) is used as an amine coupling reagent to form 5-carboxy-X-rhodamine (ROX) derivatized compounds such as proteins, nucleic acids and drugs that may be analyzed by fluorescence resonance energy transfer (FRET) and fluorescence quenching applications.Labeling reagent for preparation of charge-modified dye-labeled ddNTPs to "direct-load" DNA sequencing

Chemical Structure

ROX NHS ester, 5-isomer
ROX NHS ester, 5-isomer
CAS#209734-74-7

Theoretical Analysis

MedKoo Cat#: 558787

Name: ROX NHS ester, 5-isomer

CAS#: 209734-74-7

Chemical Formula: C37H33N3O7

Exact Mass: 631.2300

Molecular Weight: 631.69

Elemental Analysis: C, 70.35; H, 5.27; N, 6.65; O, 17.73

Price and Availability

Size Price Availability Quantity
5mg USD 550.00
25mg USD 900.00
50mg USD 1,300.00
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Related CAS #
Synonym
ROX-SE, 5-Carboxy-X-rhodamine N-succinimidyl ester
IUPAC/Chemical Name
5-Carboxy-X-rhodamine N-succinimidyl ester
InChi Key
BTTBJYLMDASSAS-UHFFFAOYSA-N
InChi Code
InChI=1S/C37H33N3O7/c41-29-11-12-30(42)40(29)47-37(45)22-9-10-23(26(19-22)36(43)44)31-27-17-20-5-1-13-38-15-3-7-24(32(20)38)34(27)46-35-25-8-4-16-39-14-2-6-21(33(25)39)18-28(31)35/h9-10,17-19H,1-8,11-16H2
SMILES Code
O=C(ON1C(CCC1=O)=O)C2=CC=C(C(C([O-])=O)=C2)C(C3=CC(CCC4)=C(N4CCC5)C5=C3O6)=C(C=C7CCC8)C6=C9C7=[N+]8CCC9
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 631.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Konopka, C.J.; Wozniak, M.; Hedhli, J.; Ploska, A.; Schwartz-Duval, A.; Siekierzycka, A.; Pan, D.; Munirathinam, G.; Dobrucki, I.T.; Kalinowski, L.; Dobrucki, L.W. Multimodal imaging of the receptor for advanced glycation end-products with molecularly targeted nanoparticles. Theranostics, 2018, 8(18), 5012–5024. doi: 10.7150/thno.24791