NIC3 is a Novel inhibitor of homodimerization of oncogenic NAC1 protein, down-regulating NAC1 protein, sensitizing drug-resistant tumor cells to conventional chemotherapy and enhancing the anti-metastatic effect of the antiangiogenic agent bevacizumab both in vitro and in vivo.
MedKoo Cat#: 533072
Name: NIC3
CAS#: 494830-67-0
Chemical Formula: C26H36N2O4
Exact Mass: 440.2675
Molecular Weight: 440.58
Elemental Analysis: C, 70.88; H, 8.24; N, 6.36; O, 14.53
The following data is based on the product molecular weight 440.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
