MedKoo Cat#: 533039 | Name: C620-0696

Description:

WARNING: This product is for research use only, not for human or veterinary use.

C620-0696 is a novel potent inhibitor of bromodomain PHD-finger transcription factor (BPTF).

Chemical Structure

C620-0696
C620-0696
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 533039

Name: C620-0696

CAS#: N/A

Chemical Formula: C24H24N4O3

Exact Mass: 416.1848

Molecular Weight: 416.48

Elemental Analysis: C, 69.21; H, 5.81; N, 13.45; O, 11.52

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Synonym
C620-0696; C-620-0696; C 620-0696; C6200696; C-6200696; C 6200696;
IUPAC/Chemical Name
5-((3-(Dimethylamino)propyl)amino)-3-((furan-3-ylmethyl)amino)-6H-anthra[1,9-cd]isoxazol-6-one
InChi Key
GHMCVYURSRCROT-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H24N4O3/c1-28(2)10-5-9-25-18-12-19(26-13-15-8-11-30-14-15)22-21-20(18)23(29)16-6-3-4-7-17(16)24(21)31-27-22/h3-4,6-8,11-12,14,25-26H,5,9-10,13H2,1-2H3
SMILES Code
O=C(C1=C2C=CC=C1)C3=C(NCCCN(C)C)C=C(NCC4=COC=C4)C5=NOC2=C53
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Methods of treating cancer with compound C620-​0696 By Leung, Lai Han Elaine; Yao, Xiao Jun; Liu, Liang; Xu, Jia Hui; Li, Ying; Wang, Qian Qian From Granted Innovation Pat. (Aust.) (2018), AU 2018100077 A4 20180215. 2. Compound C620-​0696, a new potent inhibitor targeting BPTF, the chromatin-​remodeling factor in non-​small-​cell lung cancer By Xu Jiahui; Wang Qianqian; Leung Elaine Lai Han; Li Ying; Fan Xingxing; Wu Qibiao; Yao Xiaojun; Liu Liang; Leung Elaine Lai Han; Leung Elaine Lai Han. From Frontiers of medicine (2019).