MedKoo Cat#: 581997 | Name: Decarbamylcefuroxime

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Decarbamylcefuroxime is a degradation product of Cefuroxime, and an intermediate for the synthesis of Cephalosporin antibiotics.

Chemical Structure

Decarbamylcefuroxime
Decarbamylcefuroxime
CAS#56271-94-4

Theoretical Analysis

MedKoo Cat#: 581997

Name: Decarbamylcefuroxime

CAS#: 56271-94-4

Chemical Formula: C15H15N3O7S

Exact Mass: 381.0600

Molecular Weight: 381.36

Elemental Analysis: C, 47.24; H, 3.96; N, 11.02; O, 29.37; S, 8.41

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Synonym
Decarbamylcefuroxime; EINECS 260-086-2; UNII-G9A49M069D; Cefuroxime Sodium EP Impurity A; Cefuroxime Sodium Impurity F (EP)
IUPAC/Chemical Name
(6R-(6alpha,7beta(Z)))-7-(2-Furyl(methoxyimino)acetamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
InChi Key
OUSLHGWWWMRAIG-FBCAJUAOSA-N
InChi Code
InChI=1S/C15H15N3O7S/c1-24-17-9(8-3-2-4-25-8)12(20)16-10-13(21)18-11(15(22)23)7(5-19)6-26-14(10)18/h2-4,10,14,19H,5-6H2,1H3,(H,16,20)(H,22,23)/b17-9-/t10-,14-/m1/s1
SMILES Code
O=C(C(N12)=C(CO)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 381.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Coque JJ, Pérez-Llarena FJ, Enguita FJ, Fuente JL, Martín JF, Liras P. Characterization of the cmcH genes of Nocardia lactamdurans and Streptomyces clavuligerus encoding a functional 3' hydroxymethylcephem O-carbamoyltransferase for cephamycin biosynthesis. Gene. 1995 Aug 30;162(1):21-7. PubMed PMID: 7557411.