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MedKoo Cat#: 585182 | Name: CI 26150
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CI 26150 is a coloring agent used to assess myelin repair in demyelinating diseases.

Chemical Structure

CI 26150
CI 26150
CAS#4197-25-5

Theoretical Analysis

MedKoo Cat#: 585182

Name: CI 26150

CAS#: 4197-25-5

Chemical Formula: C29H24N6

Exact Mass: 456.2062

Molecular Weight: 456.55

Elemental Analysis: C, 76.29; H, 5.30; N, 18.41

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
25g USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
CI 26150; CI-26150; CI26150; Sudan Black B; Solvent Black 3; Ceres black BN; Fat Black HB;
IUPAC/Chemical Name
2,2-dimethyl-6-((E)-(4-((E)-phenyldiazenyl)naphthalen-1-yl)diazenyl)-2,3-dihydro-1H-perimidine
InChi Key
YCUVUDODLRLVIC-VPHDGDOJSA-N
InChi Code
InChI=1S/C29H24N6/c1-29(2)30-26-14-8-13-22-25(17-18-27(31-29)28(22)26)35-34-24-16-15-23(20-11-6-7-12-21(20)24)33-32-19-9-4-3-5-10-19/h3-18,30-31H,1-2H3/b33-32+,35-34+
SMILES Code
CC(N1)(C)NC2=CC=CC3=C(/N=N/C4=C5C=CC=CC5=C(/N=N/C6=CC=CC=C6)C=C4)C=CC1=C23
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 456.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Whittington NC, Wray S. Suppression of Red Blood Cell Autofluorescence for Immunocytochemistry on Fixed Embryonic Mouse Tissue. Curr Protoc Neurosci. 2017 Oct 23;81:2.28.1-2.28.12. doi: 10.1002/cpns.35. PubMed PMID: 29058770; PubMed Central PMCID: PMC5657453. 2: Wang T, Sun W, Zhang X, Xu H, Xu F. Waterborne Polyurethane Coatings with Covalently Linked Black Dye Sudan Black B. Materials (Basel). 2017 Oct 28;10(11). pii: E1247. doi: 10.3390/ma10111247. PubMed PMID: 29143785; PubMed Central PMCID: PMC5706194. 3: Georgakopoulou EA, Tsimaratou K, Evangelou K, Fernandez Marcos PJ, Zoumpourlis V, Trougakos IP, Kletsas D, Bartek J, Serrano M, Gorgoulis VG. Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues. Aging (Albany NY). 2013 Jan;5(1):37-50. PubMed PMID: 23449538; PubMed Central PMCID: PMC3616230. 4: Fonovich TM. Sudan dyes: are they dangerous for human health? Drug Chem Toxicol. 2013 Jul;36(3):343-52. doi: 10.3109/01480545.2012.710626. Epub 2012 Sep 5. Review. PubMed PMID: 22947042. 5: Cindrova-Davies T, Fogarty NME, Jones CJP, Kingdom J, Burton GJ. Evidence of oxidative stress-induced senescence in mature, post-mature and pathological human placentas. Placenta. 2018 Aug;68:15-22. doi: 10.1016/j.placenta.2018.06.307. Epub 2018 Jun 19. PubMed PMID: 30055665; PubMed Central PMCID: PMC6083404. 6: Amin AS, Saleh HM. Extractive Spectrophotometric Determination of Nortriptyline Hydrochloride Using Sudan II, IV and Black B. Sci Pharm. 2017 Aug 17;69(2):140-149. doi: 10.3797/scipharm.aut-01-16. PubMed PMID: 28817110. 7: Evangelou K, Gorgoulis VG. Sudan Black B, The Specific Histochemical Stain for Lipofuscin: A Novel Method to Detect Senescent Cells. Methods Mol Biol. 2017;1534:111-119. PubMed PMID: 27812872. 8: Baschong W, Suetterlin R, Laeng RH. Control of autofluorescence of archival formaldehyde-fixed, paraffin-embedded tissue in confocal laser scanning microscopy (CLSM). J Histochem Cytochem. 2001 Dec;49(12):1565-72. PubMed PMID: 11724904. 9: Ineichen BV, Weinmann O, Good N, Plattner PS, Wicki C, Rushing EJ, Linnebank M, Schwab ME. Sudan black: a fast, easy and non-toxic method to assess myelin repair in demyelinating diseases. Neuropathol Appl Neurobiol. 2017 Apr;43(3):242-251. doi: 10.1111/nan.12373. Epub 2017 Mar 10. PubMed PMID: 28009439. 10: Rajabi M, Sabzalian S, Barfi B, Arghavani-Beydokhti S, Asghari A. In-line micro-matrix solid-phase dispersion extraction for simultaneous separation and extraction of Sudan dyes in different spices. J Chromatogr A. 2015 Dec 18;1425:42-50. doi: 10.1016/j.chroma.2015.11.017. Epub 2015 Nov 10. PubMed PMID: 26614171. 11: Charak BS, Advani SH, Karandikar SM, Parikh PM, Nair CN, Das Gupta A, Gopal R, Tapan KS, Nadkarni KS, Kurkure PA, et al. Sudan black B positivity in acute lymphoblastic leukemia. Acta Haematol. 1988;80(4):199-202. PubMed PMID: 2464265. 12: Yang G, Yang R, Hu J. Lysophosphatidylcholine synthesis by lipase-catalyzed ethanolysis. J Oleo Sci. 2015;64(4):443-7. doi: 10.5650/jos.ess14246. Epub 2015 Mar 11. PubMed PMID: 25766935. 13: Iwao Y. [Efficient Pharmaceutical Formulation Designs and Their Development Using Mathematical and Statistical Analysis]. Yakugaku Zasshi. 2015;135(10):1129-34. doi: 10.1248/yakushi.15-00195. Review. Japanese. PubMed PMID: 26423868. 14: Diaz-Satizabal L, Magor BG. Isolation and cytochemical characterization of melanomacrophages and melanomacrophage clusters from goldfish (Carassius auratus, L.). Dev Comp Immunol. 2015 Jan;48(1):221-8. doi: 10.1016/j.dci.2014.10.003. Epub 2014 Oct 22. PubMed PMID: 25453581. 15: Porras MA, Villar MA, Cubitto MA. Novel spectrophotometric technique for rapid determination of extractable PHA using Sudan black dye. J Biotechnol. 2017 Aug 10;255:28-32. doi: 10.1016/j.jbiotec.2017.06.012. Epub 2017 Jun 19. PubMed PMID: 28641986. 16: Oliveira VC, Carrara RC, Simoes DL, Saggioro FP, Carlotti CG Jr, Covas DT, Neder L. Sudan Black B treatment reduces autofluorescence and improves resolution of in situ hybridization specific fluorescent signals of brain sections. Histol Histopathol. 2010 Aug;25(8):1017-24. doi: 10.14670/HH-25.1017. PubMed PMID: 20552552. 17: Lanza F. Sudan black B and peroxidase positivity in cultured lymphoid cells from patients with B-type chronic lymphocytic leukemia. Haematologica. 1985 Sep-Oct;70(5):458-9. PubMed PMID: 3005143. 18: Schneider JP, Pedersen L, Mühlfeld C, Ochs M. Staining histological lung sections with Sudan Black B or Sudan III for automated identification of alveolar epithelial type II cells. Acta Histochem. 2015 Oct;117(8):675-80. doi: 10.1016/j.acthis.2015.10.005. Epub 2015 Nov 11. PubMed PMID: 26558990. 19: Niu C, Wang Z, Zuo G, Krupka TM, Ran H, Zhang P, Li P, Chen Y, Chen H, Zheng Y. Poly(Lactide-co-glycolide) ultrasonographic microbubbles carrying Sudan black for preoperative and intraoperative localization of lymph nodes. Clin Breast Cancer. 2012 Jun;12(3):199-206. doi: 10.1016/j.clbc.2012.01.005. Epub 2012 Mar 7. PubMed PMID: 22402214. 20: RODE B. Application of sudan black B technique on the pancreatic B-cells in some mammals. Nature. 1962 Jan 27;193:402. PubMed PMID: 14493085.

View History

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