MedKoo Cat#: 573988 | Name: 5-Methyluridine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.

Chemical Structure

5-Methyluridine
5-Methyluridine
CAS#1463-10-1

Theoretical Analysis

MedKoo Cat#: 573988

Name: 5-Methyluridine

CAS#: 1463-10-1

Chemical Formula: C10H14N2O6

Exact Mass: 258.0852

Molecular Weight: 258.23

Elemental Analysis: C, 46.51; H, 5.46; N, 10.85; O, 37.17

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
10g USD 350.00 2 Weeks
25g USD 550.00 2 Weeks
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Related CAS #
No Data
Synonym
5-Methyluridine, Ribothymidine, Thymine riboside
IUPAC/Chemical Name
5-Methyluridine
InChi Key
DWRXFEITVBNRMK-JXOAFFINSA-N
InChi Code
InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
SMILES Code
O=C(NC(C(C)=C1)=O)N1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 258.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Tezuka, M., Chiba, Y., Okada, S., et al. Enhancement of antitumor activity of 5-fluorouracil by ribothymidine. J. Pharmacobiodyn. 9(8), 683-687 (1986). 2. Magni, G., Fioretti, E., Ipata, P.L., et al. Bakers' yeast uridine nucleosidase. Purification, composition, and physical and enzymatic properties. J. Biol. Chem. 250(1), 9-13 (1975).