MedKoo Cat#: 532941 | Name: DMX-5804

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DMX-5804 is a novel potent and selective blocker of mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4), promoting survival of human stem cell-derived cardiomyocytes and reducing infarct size in vivo.

Chemical Structure

DMX-5804
DMX-5804
CAS#2306178-56-1

Theoretical Analysis

MedKoo Cat#: 532941

Name: DMX-5804

CAS#: 2306178-56-1

Chemical Formula: C21H19N3O3

Exact Mass: 361.1426

Molecular Weight: 361.40

Elemental Analysis: C, 69.79; H, 5.30; N, 11.63; O, 13.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
DMX-5804; DMX5804; DMX 5804
IUPAC/Chemical Name
5-(4-(2-Methoxyethoxy)phenyl)-7-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
InChi Key
FUSHFOGORKZNNQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H19N3O3/c1-26-11-12-27-17-9-7-15(8-10-17)18-13-24(16-5-3-2-4-6-16)20-19(18)21(25)23-14-22-20/h2-10,13-14H,11-12H2,1H3,(H,22,23,25)
SMILES Code
O=C1C2=C(N(C3=CC=CC=C3)C=C2C4=CC=C(OCCOC)C=C4)N=CN1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 361.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL