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MedKoo Cat#: 581978 | Name: Polyglyceryl-2 caprate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Polyglyceryl-2 caprate is alson known as PGLCP 102KC. It is a synthetic compound derived from polyglycerin and a fatty acid. The compound is vegetable in origin, making it biodegradable & toxicologically safe. It is commonly used as an emulsifier in cosmetic formula having excellent skin feeling properties bucause of its high substantiality and skin smoothening effect. This product creates fine, creamy bubbles, especially when combined with anionic surfactants. It is an excellent thickener with good thermostable viscosity. PGLCP 102KC can be used as deoactive ingredient bucause of its reaction to gram-positive bacteria.

Chemical Structure

Polyglyceryl-2 caprate
Polyglyceryl-2 caprate
CAS#156153-06-9

Theoretical Analysis

MedKoo Cat#: 581978

Name: Polyglyceryl-2 caprate

CAS#: 156153-06-9

Chemical Formula: C16H32O6

Exact Mass: 320.2200

Molecular Weight: 320.43

Elemental Analysis: C, 59.98; H, 10.07; O, 29.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Polyglyceryl-2 caprate; PGLCP 102KC; Capric acid, monoester with diglycerol; Cremercoor PG2 C10; Diglyceryl monocaprate; Dermosoft dgmc; Diglyceryl monocaprate; Polyglyceryl-2 caprate; Sunsoft Q-10D; UNII-JX7WXJ41DH.
IUPAC/Chemical Name
Decanoic acid, 3-(2,3-dihydroxypropoxy)-2-hydroxypropyl ester
InChi Key
CFTCNYXCIMEQQS-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H32O6/c1-2-3-4-5-6-7-8-9-16(20)22-13-15(19)12-21-11-14(18)10-17/h14-15,17-19H,2-13H2,1H3
SMILES Code
CCCCCCCCCC(OCC(O)COCC(O)CO)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 320.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Parikh DT, Lanjekar KJ, Rathod VK. Kinetics and thermodynamics of lipase catalysed synthesis of propyl caprate. Biotechnol Lett. 2019 Oct;41(10):1163-1175. doi: 10.1007/s10529-019-02718-x. Epub 2019 Aug 28. PubMed PMID: 31463715. 2: [French comment on article Efficacy of a paclitaxel-eluting biliary metal stent with sodium caprate in malignant biliary obstruction: a prospective randomized comparative study]. Endoscopy. 2019 Sep;51(9):904. doi: 10.1055/a-0978-5782. Epub 2019 Aug 28. French. PubMed PMID: 31461776. 3: Jørgensen JR, Jepsen ML, Nielsen LH, Dufva M, Nielsen HM, Rades T, Boisen A, Müllertz A. Microcontainers for oral insulin delivery - In vitro studies of permeation enhancement. Eur J Pharm Biopharm. 2019 Oct;143:98-105. doi: 10.1016/j.ejpb.2019.08.011. Epub 2019 Aug 16. PubMed PMID: 31425857. 4: Ba Y, Wang M, Zhang K, Chen Q, Wang J, Lv H, Jiang Y, Shi R. Intestinal Absorption Profile of Three Polygala Oligosaccharide Esters in Polygalae Radix and the Effects of Other Components in Polygalae Radix on Their Absorption. Evid Based Complement Alternat Med. 2019 Jul 2;2019:1379531. doi: 10.1155/2019/1379531. eCollection 2019. PubMed PMID: 31354847; PubMed Central PMCID: PMC6633864. 5: Roos C, Dahlgren D, Sjögren E, Sjöblom M, Hedeland M, Lennernäs H. Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions. Eur J Pharm Biopharm. 2019 Sep;142:387-395. doi: 10.1016/j.ejpb.2019.07.012. Epub 2019 Jul 12. PubMed PMID: 31306752. 6: Hvid H, Kildegaard J, Kristensen K, Porsgaard T, Jørgensen MS, Ballarín-González B, Ahnfelt-Rønne J, Hansen BF, Nishimura E. Intraintestinal and Parenteral Administration of an Insulin Analogue Leads to Comparable Activation of Signaling Downstream of the Insulin Receptor in the Small Intestine. J Diabetes Sci Technol. 2019 Jun 12:1932296819855075. doi: 10.1177/1932296819855075. [Epub ahead of print] PubMed PMID: 31189343. 7: Jang SI, Jeong S, Lee DH, Na K, Yang S, Lee DK. Safety Evaluation of Paclitaxel-Eluting Biliary Metal Stent with Sodium Caprate in Porcine Biliary Tract. Gut Liver. 2019 Apr 17;13(4):471-478. doi: 10.5009/gnl18454. PubMed PMID: 30970427; PubMed Central PMCID: PMC6622565. 8: Radloff J, Cornelius V, Markov AG, Amasheh S. Caprate Modulates Intestinal Barrier Function in Porcine Peyer's Patch Follicle-Associated Epithelium. Int J Mol Sci. 2019 Mar 20;20(6). pii: E1418. doi: 10.3390/ijms20061418. PubMed PMID: 30897851; PubMed Central PMCID: PMC6471651. 9: Worthen AJ, Irving KS, Lapitsky Y. Supramolecular Strategy Effects on Chitosan Bead Stability in Acidic Media: A Comparative Study. Gels. 2019 Feb 25;5(1). pii: E11. doi: 10.3390/gels5010011. PubMed PMID: 30823549; PubMed Central PMCID: PMC6473334. 10: Twarog C, Fattah S, Heade J, Maher S, Fattal E, Brayden DJ. Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C(10)). Pharmaceutics. 2019 Feb 13;11(2). pii: E78. doi: 10.3390/pharmaceutics11020078. Review. PubMed PMID: 30781867; PubMed Central PMCID: PMC6410172. 11: Chen J, Nan R, Wang R, Zhang L, Shi J. Ester-Producing Mechanism of Ethanol O-acyltransferase EHT1 Gene in Pichia pastoris from Shanxi Aged Vinegar. Biomed Res Int. 2019 Jan 3;2019:4862647. doi: 10.1155/2019/4862647. eCollection 2019. PubMed PMID: 30719444; PubMed Central PMCID: PMC6335666. 12: Halberg IB, Lyby K, Wassermann K, Heise T, Zijlstra E, Plum-Mörschel L. Efficacy and safety of oral basal insulin versus subcutaneous insulin glargine in type 2 diabetes: a randomised, double-blind, phase 2 trial. Lancet Diabetes Endocrinol. 2019 Mar;7(3):179-188. doi: 10.1016/S2213-8587(18)30372-3. Epub 2019 Jan 21. PubMed PMID: 30679095. 13: Jansook P, Fülöp Z, Ritthidej GC. Amphotericin B loaded solid lipid nanoparticles (SLNs) and nanostructured lipid carrier (NLCs): physicochemical and solid-solution state characterizations. Drug Dev Ind Pharm. 2019 Apr;45(4):560-567. doi: 10.1080/03639045.2019.1569023. Epub 2019 Jan 25. PubMed PMID: 30632399. 14: Oza VH, Aicher JK, Reed LK. Random Forest Analysis of Untargeted Metabolomics Data Suggests Increased Use of Omega Fatty Acid Oxidation Pathway in Drosophila Melanogaster Larvae Fed a Medium Chain Fatty Acid Rich High-Fat Diet. Metabolites. 2018 Dec 31;9(1). pii: E5. doi: 10.3390/metabo9010005. PubMed PMID: 30602659; PubMed Central PMCID: PMC6359074. 15: Khedkar A, Lebovitz H, Fleming A, Cherrington A, Jose V, Athalye SN, Vishweswaramurthy A. Impact of Insulin Tregopil and Its Permeation Enhancer on Pharmacokinetics of Metformin in Healthy Volunteers: Randomized, Open-Label, Placebo-Controlled, Crossover Study. Clin Transl Sci. 2019 May;12(3):276-282. doi: 10.1111/cts.12609. Epub 2019 Feb 12. PubMed PMID: 30592549; PubMed Central PMCID: PMC6510383. 16: Willett SA, Akoh CC. Physicochemical characterization of organogels prepared from menhaden oil or structured lipid with phytosterol blend or sucrose stearate/ascorbyl palmitate blend. Food Funct. 2019 Jan 22;10(1):180-190. doi: 10.1039/c8fo01725e. PubMed PMID: 30516201. 17: Jang SI, Lee KT, Choi JS, Jeong S, Lee DH, Kim YT, Lee SH, Yu JS, Lee DK. Efficacy of a paclitaxel-eluting biliary metal stent with sodium caprate in malignant biliary obstruction: a prospective randomized comparative study. Endoscopy. 2019 Sep;51(9):843-851. doi: 10.1055/a-0754-5763. Epub 2018 Nov 9. PubMed PMID: 30414164. 18: Yu Y, Zhang M, Hu Y, Zhao Y, Teng F, Lv X, Li J, Zhang Y, Hatch GM, Chen L. Increased Bioavailable Berberine Protects Against Myocardial Ischemia Reperfusion Injury Through Attenuation of NFκB and JNK Signaling Pathways. Int Heart J. 2018 Nov 28;59(6):1378-1388. doi: 10.1536/ihj.17-458. Epub 2018 Oct 10. PubMed PMID: 30305576. 19: Sommer E, Neubert RHH, Mentel M, Tuchscherer B, Mrestani Y, Wohlrab J. Dermal peptide delivery using enhancer molecules and colloidal carrier systems. Part III: Tetrapeptide GEKG. Eur J Pharm Sci. 2018 Nov 1;124:137-144. doi: 10.1016/j.ejps.2018.08.034. Epub 2018 Aug 27. PubMed PMID: 30165235. 20: Dahlgren D, Roos C, Lundqvist A, Tannergren C, Sjöblom M, Sjögren E, Lennernäs H. Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport. Int J Pharm. 2018 Oct 5;549(1-2):239-248. doi: 10.1016/j.ijpharm.2018.07.057. Epub 2018 Jul 26. PubMed PMID: 30055302.