MedKoo Cat#: 585162 | Name: ZAP-180013
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZAP-180013 is a Zap70 inhibitor, which inhibits interaction with ITAMs (immunoreceptor tyrosine-based activation motifs).

Chemical Structure

ZAP-180013
ZAP-180013
CAS#873080-25-2

Theoretical Analysis

MedKoo Cat#: 585162

Name: ZAP-180013

CAS#: 873080-25-2

Chemical Formula: C19H17Cl2N3O4S

Exact Mass: 453.0317

Molecular Weight: 454.32

Elemental Analysis: C, 50.23; H, 3.77; Cl, 15.61; N, 9.25; O, 14.09; S, 7.06

Price and Availability

Size Price Availability Quantity
25mg USD 250.00 2 Weeks
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,450.00 2 Weeks
1g USD 3,450.00 2 Weeks
2g USD 5,850.00 2 Weeks
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Related CAS #
No Data
Synonym
ZAP 180013; ZAP180013; ZAP-180013
IUPAC/Chemical Name
5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide
InChi Key
GTWKIPDKVRLUKN-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H17Cl2N3O4S/c1-2-29(26,27)19-22-10-16(21)17(23-19)18(25)24(12-15-4-3-9-28-15)11-13-5-7-14(20)8-6-13/h3-10H,2,11-12H2,1H3
SMILES Code
O=C(C1=NC(S(=O)(CC)=O)=NC=C1Cl)N(CC2=CC=C(Cl)C=C2)CC3=CC=CO3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 454.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Visperas et al (2017) Identification of inhibitors of the association of ZAP-70 with the T-cell receptor by high-throughput screen. SLAS.Discov. 22 324 PMID: 27932698