GSK3491943 is a potent TRPV4 inhibitor with IC50 = 3.2 nM. GSK3491943 is a potential agent for the treatment of heart failure and respiratory diseases.
MedKoo Cat#: 555657
Name: GSK3491943
CAS#: 2215853-96-4
Chemical Formula: C18H16Cl2N2O5S
Exact Mass: 442.0157
Molecular Weight: 443.30
Elemental Analysis: C, 48.77; H, 3.64; Cl, 15.99; N, 6.32; O, 18.05; S, 7.23
The following data is based on the product molecular weight 443.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
