Synonym
Dapiramicin; Antibiotic SF 1917; SF 1917; SF1917; SF-1917
IUPAC/Chemical Name
1H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 2-((6-deoxy-4-O-(4-O-methyl-beta-D-glucopyranosyl)-alpha-D-glucopyranosyl)amino)-4-methoxy-
InChi Key
ZBQJUUDIPOFIAD-CQTPLZCRSA-N
InChi Code
InChI=1S/C21H29N5O10/c1-7-15(36-20-14(31)12(29)16(32-2)9(6-27)35-20)11(28)13(30)19(34-7)26-21-24-17-10(18(25-21)33-3)8(4-22)5-23-17/h5,7,9,11-16,19-20,27-31H,6H2,1-3H3,(H2,23,24,25,26)/t7-,9-,11-,12-,13-,14-,15-,16-,19+,20+/m1/s1
SMILES Code
N#CC1=CN=C2NC(N[C@@H]3[C@@H]([C@H]([C@@H]([C@@H](C)O3)O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)OC)O)O)O)O)=NC(OC)=C21
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
511.49
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Shomura T, Nishizawa N, Iwata M, Yoshida J, Ito M, Amano S, Koyama M, Kojima M, Inouye S. Studies on a new nucleoside antibiotic, dapiramicin. I. Producing organism, assay method and fermentation. J Antibiot (Tokyo). 1983 Oct;36(10):1300-4. PubMed PMID: 6643279.
2: Nishizawa N, Kondo Y, Koyama M, Omoto S, Iwata M, Tsuruoka T, Inouye S. Studies on a new nucleoside antibiotic, dapiramicin. II. Isolation, physico-chemical and biological characterization. J Antibiot (Tokyo). 1984 Jan;37(1):1-5. PubMed PMID: 6546562.