MedKoo Cat#: 555624 | Name: TP353
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TP353 is a CDK7 inhibitor.

Chemical Structure

TP353
TP353
CAS#1253799-29-9

Theoretical Analysis

MedKoo Cat#: 555624

Name: TP353

CAS#: 1253799-29-9

Chemical Formula: C35H30FNO3

Exact Mass: 531.2210

Molecular Weight: 531.63

Elemental Analysis: C, 79.08; H, 5.69; F, 3.57; N, 2.63; O, 9.03

Price and Availability

Size Price Availability Quantity
50mg USD 250.00 2 Weeks
100mg USD 450.00 2 Weeks
200mg USD 750.00 2 Weeks
500mg USD 1,450.00 2 Weeks
1g USD 2,450.00 2 Weeks
2g USD 4,450.00 2 Weeks
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Related CAS #
No Data
Synonym
TP353; TP-353; TP 353;
IUPAC/Chemical Name
Phenyl 2-(benzyloxy)-3-(dibenzylamino)-5-fluoro-6-methylbenzoate
InChi Key
VRXGVVAMXZXKNA-UHFFFAOYSA-N
InChi Code
InChI=1S/C35H30FNO3/c1-26-31(36)22-32(37(23-27-14-6-2-7-15-27)24-28-16-8-3-9-17-28)34(39-25-29-18-10-4-11-19-29)33(26)35(38)40-30-20-12-5-13-21-30/h2-22H,23-25H2,1H3
SMILES Code
O=C(OC1=CC=CC=C1)C2=C(C)C(F)=CC(N(CC3=CC=CC=C3)CC4=CC=CC=C4)=C2OCC5=CC=CC=C5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 531.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Hu S, Zhao J, Fang S, Guo K, Qi W, Liu H. Neurotoxic effects of chloroquine and its main transformation product formed after chlorination. Sci Total Environ. 2024 Jan 15;908:168043. doi: 10.1016/j.scitotenv.2023.168043. Epub 2023 Oct 26. PMID: 37898196.