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MedKoo Cat#: 585133 | Name: Droxicainide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Droxicainide is an antiarrhythmic agent.

Chemical Structure

Droxicainide
Droxicainide
CAS#78289-26-6

Theoretical Analysis

MedKoo Cat#: 585133

Name: Droxicainide

CAS#: 78289-26-6

Chemical Formula: C16H24N2O2

Exact Mass: 276.1838

Molecular Weight: 276.38

Elemental Analysis: C, 69.53; H, 8.75; N, 10.14; O, 11.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Droxicainide; ALS-1249; S-1249
IUPAC/Chemical Name
2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-(2-hydroxyethyl)-
InChi Key
NVASAXNGHUPVJX-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H24N2O2/c1-12-6-5-7-13(2)15(12)17-16(20)14-8-3-4-9-18(14)10-11-19/h5-7,14,19H,3-4,8-11H2,1-2H3,(H,17,20)
SMILES Code
O=C(C1N(CCO)CCCC1)NC2=C(C)C=CC=C2C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 276.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Faria DB, Cheung WM, Ribeiro LG, Maroko PR. Effects of lidocaine and droxicainide on myocardial necrosis: a comparative study. J Am Coll Cardiol. 1983 Jun;1(6):1447-52. PubMed PMID: 6853899. 2: Helgesen KG, Kristiansen O, Refsum H. Comparison of electrophysiological and mechanical effects of droxicainide and lidocaine on heart muscle isolated from rats. Acta Pharmacol Toxicol (Copenh). 1984 Oct;55(4):303-7. PubMed PMID: 6507117. 3: Aberg G, af Ekenstam B, Smith E. Pharmacological studies on droxicainide, a new antiarrhythmic agent. Arzneimittelforschung. 1983;33(5):706-10. PubMed PMID: 6683549. 4: Aberg G, Ronfeld R, Smith E. The acute antiarrhythmic effects of droxicainide and lidocaine in unanesthetized dogs. J Cardiovasc Pharmacol. 1984 Mar-Apr;6(2):355-60. PubMed PMID: 6200728.