E09241 | CAS#1043110-13-9

MedKoo Cat#: 532720 | Name: E09241

Description:

WARNING: This product is for research use only, not for human or veterinary use.

E09241 is a novel OPG/RANKL upregulator, increasing OPG expression without affecting RANKL expression, promoting osteoblast differentiation while inhibiting osteoclast differentiation, regulating OPG expression through canonical Wnt/β-catenin signaling.

Chemical Structure

E09241

CAS#1043110-13-9

Theoretical Analysis

MedKoo Cat#: 532720

Name: E09241

CAS#: 1043110-13-9

Chemical Formula: C11H9ClN2O2

Exact Mass: 236.0353

Molecular Weight: 236.66

Elemental Analysis: C, 55.83; H, 3.83; Cl, 14.98; N, 11.84; O, 13.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

E09241; E-09241; E 09241;

IUPAC/Chemical Name

5-Chloro-N-(4-methylpyridin-2-yl)furan-2-carboxamide

InChi Key

XUZSJAATNRKRPD-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H9ClN2O2/c1-7-4-5-13-10(6-7)14-11(15)8-2-3-9(12)16-8/h2-6H,1H3,(H,13,14,15)

SMILES Code

O=C(C1=CC=C(Cl)O1)NC2=NC=CC(C)=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 236.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Han X, Gong S, Li N, Wang X, Liu P, Xu Y, He X, Jiang W, Si S. A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy-Related Bone Loss in Rats. Front Pharmacol. 2019 Mar 11;10:103. doi: 10.3389/fphar.2019.00103. eCollection 2019. PubMed PMID: 30914947; PubMed Central PMCID: PMC6421503.