Adonixanthin | CAS# 4418-73-9 | Biochemical

MedKoo Cat#: 573926 | Name: Adonixanthin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Adonixanthin is a biochemical that activates Nrf2 to prevent light-induced photoreceptor degeneration.

Chemical Structure

Adonixanthin

CAS#4418-73-9

Theoretical Analysis

MedKoo Cat#: 573926

Name: Adonixanthin

CAS#: 4418-73-9

Chemical Formula: C40H54O3

Exact Mass: 582.4073

Molecular Weight: 582.87

Elemental Analysis: C, 82.43; H, 9.34; O, 8.23

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Adonixanthin, All-trans-beta-doradexanthin, beta-Doradexanthin, Doradexanthin

IUPAC/Chemical Name

(S)-6-hydroxy-3-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-((R)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl)-2,4,4-trimethylcyclohex-2-en-1-one

InChi Key

YECXHLPYMXGEBI-ZNQVSPAOSA-N

InChi Code

1S/C40H54O3/c1-28(17-13-19-30(3)21-23-35-32(5)25-34(41)26-39(35,7)8)15-11-12-16-29(2)18-14-20-31(4)22-24-36-33(6)38(43)37(42)27-40(36,9)10/h11-24,34,37,41-42H,25-27H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,28-15+,29-16+,30-19+,31-20+/t34-,37+/m1/s1

SMILES Code

C\C(=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C(=O)[C@@H](O)CC1(C)C)\C=C\C=C(/C)\C=C\C2=C(C)C[C@@H](O)CC2(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 582.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Iwata S, Imai T, Shimazawa M, Ishibashi T, Hayashi M, Hara H, Nakamura S. Protective effects of the astaxanthin derivative, adonixanthin, on brain hemorrhagic injury. Brain Res. 2018 Nov 1;1698:130-138. doi: 10.1016/j.brainres.2018.08.009. Epub 2018 Aug 6. PubMed PMID: 30092231. 2: Inoue Y, Shimazawa M, Nagano R, Kuse Y, Takahashi K, Tsuruma K, Hayashi M, Ishibashi T, Maoka T, Hara H. Astaxanthin analogs, adonixanthin and lycopene, activate Nrf2 to prevent light-induced photoreceptor degeneration. J Pharmacol Sci. 2017 Jul;134(3):147-157. doi: 10.1016/j.jphs.2017.05.011. Epub 2017 Jun 21. PubMed PMID: 28689962. 3: Maoka T, Yasui H, Ohmori A, Tokuda H, Suzuki N, Osawa A, Shindo K, Ishibashi T. Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin. J Oleo Sci. 2013;62(3):181-6. PubMed PMID: 23470446.