MedKoo Cat#: 558718 | Name: MMV006764

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MMV006764 is the first small-molecule anti-plasmodial agent which disrupts rosetting, simultaneously restoring microcirculation and reducing parasite load.

Chemical Structure

MMV006764
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 558718

Name: MMV006764

CAS#: NONE

Chemical Formula: C19H22BrNO6

Exact Mass: 439.0631

Molecular Weight: 440.29

Elemental Analysis: C, 51.83; H, 5.04; Br, 18.15; N, 3.18; O, 21.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MMV-006764; MMV 006764; MMV006764; GNF Pf-4926; GNF-Pf 4926; GNF-Pf-4926
IUPAC/Chemical Name
Dimethyl 4-(3-bromo-4-ethoxy-5-methoxyphenyl)-1-methyl-4H-pyridine-3,5-dicarboxylate
InChi Key
GHWXGIMICMXCPZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H22BrNO6/c1-6-27-17-14(20)7-11(8-15(17)24-3)16-12(18(22)25-4)9-21(2)10-13(16)19(23)26-5/h7-10,16H,6H2,1-5H3
SMILES Code
O=C(C1=CN(C)C=C(C(OC)=O)C1C2=CC(OC)=C(OCC)C(Br)=C2)OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 440.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ch'ng JH, Moll K, Quintana Mdel P, Chan SC, Masters E, Moles E, Liu J, Eriksson AB, Wahlgren M. Rosette-Disrupting Effect of an Anti-Plasmodial Compound for the Potential Treatment of Plasmodium falciparum Malaria Complications. Sci Rep. 2016 Jul 11;6:29317. doi: 10.1038/srep29317. PubMed PMID: 27403804; PubMed Central PMCID: PMC4941523.