Ipidacrine is a ring-constricted derivative of tacrine (Cognex) and a reversible acetylcholinesterase inhibitor used in memory disorders. Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.
MedKoo Cat#: 573853
Name: Ipidacrine
CAS#: 62732-44-9
Chemical Formula: C12H16N2
Exact Mass: 188.1313
Molecular Weight: 188.27
Elemental Analysis: C, 76.55; H, 8.57; N, 14.88
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 25.0 | 132.79 | |
| DMSO | 25.0 | 132.79 | |
| DMSO:PBS (pH 7.2) (1:3) | 0.3 | 1.33 |
The following data is based on the product molecular weight 188.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
