KK-S6 | Circadian Clock Modulator

MedKoo Cat#: 558671 | Name: KK-S6

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KK-S6 is a circadian clock modulator which controls BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism.

Chemical Structure

KK-S6

CAS#NONE

Theoretical Analysis

MedKoo Cat#: 558671

Name: KK-S6

CAS#: NONE

Chemical Formula: C23H26O4

Exact Mass: 366.1831

Molecular Weight: 366.46

Elemental Analysis: C, 75.38; H, 7.15; O, 17.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

KKS6; KK S6; KK-S6

IUPAC/Chemical Name

2-(3,4-Dimethoxyphenyl)-1-(2-methoxy-4-(2-methylbut-3-yn-2-yl)phenyl)propan-1-one

InChi Key

IGHQCZSHPLFECF-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H26O4/c1-8-23(3,4)17-10-11-18(20(14-17)26-6)22(24)15(2)16-9-12-19(25-5)21(13-16)27-7/h1,9-15H,2-7H3

SMILES Code

CC(C1=CC=C(OC)C(OC)=C1)C(C2=CC=C(C(C#C)(C)C)C=C2OC)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 366.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lee J, Lee S, Chung S, Park N, Son GH, An H, Jang J, Chang DJ, Suh YG, Kim K. Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism. Biochem Biophys Res Commun. 2016 Jan 15;469(3):580-6. doi: 10.1016/j.bbrc.2015.12.030. Epub 2015 Dec 12. PubMed PMID: 26692477.