CycLuc1 is a synthetic luciferin analog designed to improve the performance of bioluminescence imaging (BLI) in live cells and animals. It serves as a substrate for firefly luciferase (Fluc), exhibiting enhanced cell permeability and increased light output compared to native D-luciferin. Its mechanism involves oxidation by luciferase in the presence of ATP and oxygen, producing a more intense and sustained bioluminescent signal, making it valuable for sensitive in vivo imaging applications in molecular and cellular biology.
MedKoo Cat#: 585042
Name: CycLuc 1
CAS#: 1247879-16-8
Chemical Formula: C13H11N3O2S2
Exact Mass: 305.0293
Molecular Weight: 305.37
Elemental Analysis: C, 51.13; H, 3.63; N, 13.76; O, 10.48; S, 21.00
The following data is based on the product molecular weight 305.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
