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MedKoo Cat#: 573770 | Name: AM-7359 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AM-7359 HCl is a novel oxazolidinone with low resistance potential and potent activity against drug resistant pathogens.

Chemical Structure

AM-7359 HCl
AM-7359 HCl
CAS#831201-17-3

Theoretical Analysis

MedKoo Cat#: 573770

Name: AM-7359 HCl

CAS#: 831201-17-3

Chemical Formula: C23H21ClFN7O2

Exact Mass: 481.1429

Molecular Weight: 481.92

Elemental Analysis: C, 57.32; H, 4.39; Cl, 7.36; F, 3.94; N, 20.35; O, 6.64

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AM-7359 HCl , AM-7359 hydrochloride
IUPAC/Chemical Name
3-Azabicyclo(3.1.0)hexane-6-carbonitrile, 6-(5-(2-fluoro-4-((5R)-2-oxo-5-(1H-1,2,3-triazol-1-ylmethyl)-3-oxazolidinyl)phenyl)-2-pyridinyl)-, monohydrochloride, (1alpha,5alpha,6beta)-
InChi Key
LMTBFEVMESUQCJ-KGLJNFNSSA-N
InChi Code
1S/C23H20FN7O2.ClH/c24-20-7-15(31-12-16(33-22(31)32)11-30-6-5-28-29-30)2-3-17(20)14-1-4-21(27-8-14)23(13-25)18-9-26-10-19(18)23;/h1-8,16,18-19,26H,9-12H2;1H/t16-,18-,19+,23+;/m0./s1
SMILES Code
Cl.Fc1cc(ccc1c2ccc(nc2)C3(C#N)[C@@H]4CNC[C@H]34)N5C[C@H](Cn6ccnn6)OC5=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 481.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gill CJ, Abruzzo GK, Flattery AM, Misura AS, Bartizal K, Hickey EJ. In vivo efficacy of a novel oxazolidinone compound in two mouse models of infection. Antimicrob Agents Chemother. 2007 Sep;51(9):3434-6. Epub 2007 Jul 2. PubMed PMID: 17606686; PubMed Central PMCID: PMC2043186. 2: Overbye KM, Mordekhay D. AM-7359--a novel oxazolidinone with low resistance potential and potent activity against drug resistant pathogens. J Chemother. 2007 Jun;19(3):249-55. PubMed PMID: 17594918.