MedKoo Cat#: 565778 | Name: M1001
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

M1001 is a novel allosteric agonist of hypoxia-inducible factor-2α subunit (hif-2α), significantly displacing pocket residue y281

Chemical Structure

M1001
M1001
CAS#874590-32-6

Theoretical Analysis

MedKoo Cat#: 565778

Name: M1001

CAS#: 874590-32-6

Chemical Formula: C17H17N3O2S

Exact Mass: 327.1041

Molecular Weight: 327.40

Elemental Analysis: C, 62.37; H, 5.23; N, 12.83; O, 9.77; S, 9.79

Price and Availability

Size Price Availability Quantity
100mg USD 650.00 2 Weeks
250mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
M1001; M 1001; M-1001
IUPAC/Chemical Name
3-((2-(Pyrrolidin-1-yl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide
InChi Key
LONXCUOJVJLTIP-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H17N3O2S/c21-23(22)16-10-4-1-7-13(16)17(19-23)18-14-8-2-3-9-15(14)20-11-5-6-12-20/h1-4,7-10H,5-6,11-12H2,(H,18,19)
SMILES Code
O=S1(N=C(NC2=CC=CC=C2N3CCCC3)C4=CC=CC=C41)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 327.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: den Bakker HC, Manuel CS, Fortes ED, Wiedmann M, Nightingale KK. Genome sequencing identifies Listeria fleischmannii subsp. coloradonensis subsp. nov., isolated from a ranch. Int J Syst Evol Microbiol. 2013 Sep;63(Pt 9):3257-68. doi: 10.1099/ijs.0.048587-0. Epub 2013 Mar 22. PubMed PMID: 23524352. 2: Wang SL, Shieh ST, Pai CS. Production, purification and characterization of two proteinaceous hen-egg-white lysozyme inhibitors from Pseudomonas aeruginosa M-1001. Proc Natl Sci Counc Repub China B. 1995 Jul;19(3):166-75. PubMed PMID: 7480363. 3: Hukami K. [An attempt at training color vision defectives with Sanvista (M-1001)]. Nippon Ganka Gakkai Zasshi. 1966 Jun;70(6):589-92. Japanese. PubMed PMID: 5297148. 4: Perloff D, Sokolow M, Cowan R. Clinical relevance of ambulatory blood pressure measurements. Biotelem Patient Monit. 1981;8(1-2):67-80. PubMed PMID: 7295924. 5: Wang SL, Pai CS, Shieh ST. Production of lytic enzyme from Pseudomonas aeruginosa M-1001. Proc Natl Sci Counc Repub China B. 1995 Oct;19(4):216-24. PubMed PMID: 8742619.