MedKoo Cat#: 565708 | Name: DC360

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DC360 is a novel fluorescent retinoic acid analogue as a probe for biochemical and intracellular characterization of retinoid signalling pathways, strongly binding to cellular retinoid binding protein ii (crabpii),

Chemical Structure

DC360
DC360
CAS#2324152-25-0v

Theoretical Analysis

MedKoo Cat#: 565708

Name: DC360

CAS#: 2324152-25-0v

Chemical Formula: C23H23NO2

Exact Mass: 345.1729

Molecular Weight: 345.44

Elemental Analysis: C, 79.97; H, 6.71; N, 4.05; O, 9.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
DC360; DC 360; DC-360
IUPAC/Chemical Name
4-((1-Isopropyl-4,4-dimethyl-1,4-dihydroquinolin-6-yl)ethynyl)benzoic acid
InChi Key
HXWVRWZLWIKKOS-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H23NO2/c1-16(2)24-14-13-23(3,4)20-15-18(9-12-21(20)24)6-5-17-7-10-19(11-8-17)22(25)26/h7-16H,1-4H3,(H,25,26)
SMILES Code
O=C(O)C1=CC=C(C#CC2=CC3=C(N(C(C)C)C=CC3(C)C)C=C2)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 345.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chisholm DR, Tomlinson CWE, Zhou GL, Holden C, Affleck V, Lamb R, Newling K, Ashton P, Valentine R, Redfern C, Erostyák J, Makkai G, Ambler CA, Whiting A, Pohl E. Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways. ACS Chem Biol. 2019 Mar 15;14(3):369-377. doi: 10.1021/acschembio.8b00916. Epub 2019 Feb 13. PubMed PMID: 30707838.