PKZ18 is a novel antibiotic against a unique trna-mediated regulation of transcription in gram-positive bacteria, significantly inhibiting in vivo transcription of glycyl-trna synthetase mrna, also inhibiting in vivo translation of the s. aureus threonyl-trna synthetase protein
MedKoo Cat#: 565676
Name: PKZ18
CAS#: 849658-87-3
Chemical Formula: C22H26N2O3S
Exact Mass: 398.1664
Molecular Weight: 398.52
Elemental Analysis: C, 66.31; H, 6.58; N, 7.03; O, 12.04; S, 8.04
The following data is based on the product molecular weight 398.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
